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860861 | CER1(d18:1/28:0/18:2)

N-[28-linoleoyloxy octacosanoyl]-D-erythro-sphingosine

CER1(d18:1/28:0/18:2)

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Size SKU Packaging Price
1mg 860861P-1mg 860861P-1mg 1 x 1mg $428.30
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Info

CER1(d18:1/28:0/18:2)

N-[28-linoleoyloxy octacosanoyl]-D-erythro-sphingosine

N-[28-linoleoyloxy octacosanoyl]-D-erythro-sphingosine, or CER1(d18:1/28:0/18:2), is a specialized sphingolipid essential for maintaining skin barrier integrity and hydration. As a key component of the stratum corneum (SC)—the outermost layer of the skin—ceramides play a vital role in regulating water retention and protecting against environmental stressors. The lipid matrix of the SC is primarily composed of ceramides, free fatty acids, and cholesterol, which form a highly organized structure that prevents excessive transepidermal water loss.

Dysfunction in ceramide composition has been linked to a number of dermatological conditions, including lamellar ichthyosis, atopic dermatitis, and psoriasis. 

Application

CER1(d18:1/28:0/18:2) serves as an internal standard for high-throughput lipidomics studies, enabling precise quantification of ceramide species in biological samples. It is also used to investigate the role of ceramides in skin hydration, barrier function, and dermatological disease mechanisms. Additionally, CER1(d18:1/28:0/18:2) supports research in advanced skincare and dermatological therapeutics that work to restore lipid balance in compromised skin.

Packaging

Avanti Research™ provides CER1(d18:1/28:0/18:2) in 1mg powder, offering customized options to meet diverse research and formulation needs.

With over 50 years of expertise in lipid and sphingolipid innovation, Avanti ensures the highest purity and consistency to empower researchers in their discoveries.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula

C64H121NO5

Percent Composition

C 78.07%, H 12.39%, N 1.42%, O 8.12%

Stability
3 Months
Storage Temperature
-20°C
CAS Number
917233-21-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
984.67
Exact Mass
983.92
Synonyms
EOS
Downloads
Certificates of Analysis

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