Small Molecule Delivery
Your small molecule delivery partner
Small molecule drugs already save numerous lives every year and together we can protect even more people by developing next-generation innovative formulations.
We aim to grow and outperform in the market sectors we serve by paying attention to the needs of our customers and using our technical and manufacturing expertise. Our unique portfolio for small molecule delivery can support you from innovative research to large-scale, commercial production. Let's bring the next generation of small molecule drugs to the world together.
It starts with Avanti Research...
Think of our research-use-only (RUO) portfolio as your ultimate toolbox for liposomal and other lipid-based formulation development. With a wide range of phospholipids, charged lipids, functionalized lipids, and sterols, you can build a delivery system tailored to your specific needs.
At this early stage in your project, you'll want a wide selection of reagents with purity you can trust, and you'll need them fast. Avanti Research accelerates your research by consistently delivering on these three key elements.
Browse our selection of lipid-based delivery system components below!
Phospholipids
Phospholipids are the main component in many lipid-based delivery systems due to their tendency to self-assemble into spherical vesicles in an aqueous solution. Avanti offers a wide variety of saturated vs unsaturated, short vs long, and natural vs synthetic phospholipids for your formulation studies.
Sterols
Cholesterol has historically been the steroid of choice to improve the rigidity and stability of lipid-based delivery systems. But that's not the only choice you have! We have a wide selection of sterols that may change physicochemical and performance outcomes for your formulation and application.
Cationic Lipids
Cationic lipids are used to encapsulate negatively charged payloads through electrostatic interactions, typical in nucleic acid delivery systems but also effective for negatively charged molecules. We offer DOTAP, the most common cationic lipid in liposomal formulations, but we have plenty of others to choose from as well.
Targeting Lipids
Ligand-mediated targeting can be used to actively target specific cells. We offer a wide range of functionalized lipids that allow you to take advantage of ligand-mediated targeting by conjugating peptides, antibodies, and more to the outer surface of your lipid-based delivery system.
Anionic Lipids
Although anionic lipid systems are not extensively used as drug carriers, they do have advantages in some applications such as transdermal drug delivery. The negative charge prevents aggregation and increases absorbance in the reticulo-endothelial system. Check out our offering today!
We also offer services to help support your research formulations. Learn more about our custom synthesis and formulations development services by clicking on the links below!
We're a research partner that thinks like you. Discover the difference
Custom lipid synthesis
Discover the difference...then Croda Pharma carries you further
When you're ready to take your research project to the next stage, Croda Pharma is ready to guide you through a seamless transition. Our AvantiTM range of GMP lipids are only a portion of the specialty ingredients we have to offer. We're a market leader as the exclusive supplier of Super RefinedTM excipients, developed to optimize stability and improve performance of your pharmaceutical formulations.
But it's not just about the high quality ingredients that we supply. When you partner with us, you partner directly with our technical teams, enabling faster communication and enhanced collaboration. We're here to support your development of innovative formulations and optimize your drug delivery system.
Learn more about the benefits you'll get when you choose us as your small molecule delivery partner by clicking the button below! Or keep scrolling to discover the solutions we offer across a wide variety of administration routes.