Sphingomyelin

Sphingomyelin (SM) is the most abundant sphingolipid found in eukaryotes and is a major component of cell membranes. Increased amounts of SM are found in the central nervous system (CNS) especially in the myelin sheath surrounding neuronal axons. SM has been linked to roles in cell processes, regulation of inflammatory responses, and signal transduction. Due to its increased abundance in the CNS and neuronal networks, SM may also play an important role in brain development and cognitive development. SM is also present in breast milk and while little is known about its function, a recent study indicated that it does play a significant role in infant nutrition. Avanti offers natural sphingomyelin from sources such as chicken egg, porcine brain, and bovine milk, as well as many synthetic derivatives.

Schneider N., Hauser J., Oliveira M., Cazaubon E., Mottaz S., O’Neill B., Steiner P., Deoni S. (2019) Sphingomyelin in Brain and Cognitive Development: Preliminary Data. eNeuro DOI: 10.1523/ENEURO.0421-18.2019

  • Natural
    • BUY
      860061 - Egg SM
    • BUY
      860062 - Brain SM
    • BUY
      860063 - Milk SM
  • Synthetic SM & Derivatives
    • BUY
      860580 - 02:0 SM (d18:1/2:0)
    • BUY
      860582 - 06:0 SM (d18:1/6:0)
    • BUY
      860583 - 12:0 SM (d18:1/12:0)
    • BUY
      860584 - 16:0 SM (d18:1/16:0)
    • BUY
      860585 - 17:0 SM (d18:1/17:0)
    • BUY
      860586 - 18:0 SM (d18:1/18:0)
    • BUY
      860587 - 18:1 SM (d18:1/18:1(9Z))
    • BUY
      860592 - 24:0 SM
    • BUY
      860593 - 24:1 SM
    • BUY
      860600 - Lyso SM (d18:1)
    • BUY
      860620 - Lyso SM (dihydro) (d18:0)
    • BUY
      860639 - Lyso SM-d7
    • BUY
      860656 - Lyso SM (d17:1)
    • BUY
      860683 - 12:0 Dihydro SM (d18:0/12:0)
    • BUY
      860684 - 16:1 SM (d18:1/16:1(9Z))
    • BUY
      860688 - 14:0 SM (d18:1/14:0)
    • BUY
      860725 - 28:0 SM (d18:1/28:0)
    • BUY
      860773 - Lyso SM-509
  • Methylated Sphingomyelin
    • BUY
      860756 - 3-O-methyl Lyso SM (d18:1)
    • BUY
      860758 - 3-O-methyl-N-methyl Lyso SM (d18:1)
    • BUY
      860759 - 3-N-methyl Lyso SM (d18:1)