Formulations Development
Our formulations experts can help develop a suitable formulation for your lipid-based delivery system. With the vast library of Avanti lipids and state-of-the-art equipment at our disposal, this experienced team can produce cargo-loaded, surface-labeled, PEGylated, fluorescent, and other lipid formulations, or custom lipid blends for use in your delivery or diagnostic application.
Let us help you do amazing things with our lipids!
The product development cycle generally has the following steps prior to product launch.
- Technology Transfer
- Formulation Screening and Optimization
- R&D Material Production
- Process Development and Scale-up
- Production of Clinical Materials
- Further Process Scale-up and Optimization
- Manufacturing of Commercial-scale Bulk Product
Avanti can provide expert assistance at any point along this path. Our team of formulation experts is ready to help you translate your product ideas into reality, offering support and guidance from initial concept through to full-scale production. Contact us today to discuss how Avanti can be a vital partner in your product development journey.
AT THE R&D STAGE
Our formulations experts excel in producing lipid formulations tailored to your project needs. Whether you need assistance designing a lipid-based drug delivery system or scaling up your process, we have the expertise to deliver exceptional results. If the ideal lipid isn’t in our catalog, our synthesis team can prepare it for you.
- Offer formulation expertise and assist in the design of lipid-based formulations
- Provide the full Avanti lipid catalog for custom formulations as small as 25 mg
- Provide custom synthesis of lipids for your formulation
- Make custom lipid formulations to meet your specifications or prepare custom lipid blends
- Provide lipid-based drug delivery systems that encapsulate, conjugate, or complex APIs, nucleic acids, proteins, small molecules, antibodies, etc.
- Produce 250 µL – 50 L lipid formulations using:
AT THE CLINICAL STAGE
The clinical process starts with the assignment of a dedicated Project Manager, ensuring that your project is completed within your expected timeline. Your Project Manager works in partnership with you through the following process.
- Scaling up small-scale manufacturing to larger-scale (1 L – 55 L batches)
- Manufacturing clinical trial materials in our animal product-free, cGMP manufacturing suite
- Producing liposomes or nanoparticles in our cGMP manufacturing suite
- Recommendations for sterile-filtration facility for parenteral products
- Coordinating inter-departmental efforts, including analytical method development, qualification and validation, stability, and regulatory support
- Alternatively, we can help facilitate the technology transfer to a facility of your choice.
AT THE COMMERCIAL STAGE
Our formulations experts support oral formulations for commercial production and ensure a seamless transfer of parenteral products to commercial production at sterile lipid formulation product manufacturers.
- Scale up manufacturing to meet your product needs
- Deliver the same care to your product as we do to our lipids, maintaining industry-leading quality for over 50 years
- Ensure seamless transition to commercial drug product manufacturing
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Why should you use lipids in your formulations?
Want to make your own liposomes, but not sure where to start?
There are many possible lipid formulations suitable for liposome preparations.
Click here for more information!
Are you ready to speak with our formulations experts?
Click here to contact us!Liposomes and Nanoparticles.
What happens when your research partner is with you all the way?
Click here for our Formulations brochure!