890850 | 18:1 DAP

1,2-dioleoyl-3-dimethylammonium-propane (DODAP)

18:1 DAP

Chloroform

Size SKU Packaging Price
25mg 890850C-25mg 890850C-25mg 1 x 25mg 10mg/mL 2.5mL $223.75
200mg 890850C-200mg 890850C-200mg 2 x 100mg 25mg/mL 4mL $468.00
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Oil

Size SKU Packaging Price
25mg 890850O-25mg 890850O-25mg 1 x 25mg $223.75 223.75
200mg 890850O-200mg 890850O-200mg 2 x 100mg $468.00 468
Request Bulk Pricing

Info

18:1 DAP

1,2-dioleoyl-3-dimethylammonium-propane (DODAP)

Data
Hygroscopic
No
Light Sensitive
Yes
Molecular Formula
C41H77NO4
Percent Composition
C 75.99%, H 11.98%, N 2.16%, O 9.88%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
127512-29-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
648.054
Exact Mass
647.585
Synonyms
1,2-di-(9Z-octadecenoyl)-3-dimethylammonium-propane
DODAP
Solubility in Different Solvents
Soluble in ethanol, DMSO, and Chloroform:Methanol:Water (65:25:4) at 5mg/mL
References

Cheng Q, Wei T, Farbiak L, Johnson LT, Dilliard SA, Siegwart DJ. Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR-Cas gene editing. Nat Nanotechnol. 2020 Apr;15(4):313-320. doi: 10.1038/s41565-020-0669-6. Epub 2020 Apr 6. PMID: 32251383.

PubMed ID: 32251383

Fattore L, Campani V, Ruggiero CF, Salvati V, Liguoro D, Scotti L, Botti G, Ascierto PA, Mancini R, De Rosa G, Ciliberto G. In Vitro Biophysical and Biological Characterization of Lipid Nanoparticles Co-Encapsulating Oncosuppressors miR-199b-5p and miR-204-5p as Potentiators of Target Therapy in Metastatic Melanoma. Int J Mol Sci. 2020 Mar 12;21(6):1930. doi: 10.3390/ijms21061930. PMID: 32178301; PMCID: PMC7139872.

PubMed ID: 32178301
Certificates of Analysis

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