890899 | DODMA
1,2-dioleyloxy-3-dimethylaminopropane

DODMA
1,2-dioleyloxy-3-dimethylaminopropane
Cationic lipids such as DODMA are considered non-viral carriers for gene therapy. DODMA is used for the preparation of cationic liposomes or lipid nanoparticles (LNP) needing a neutral or low zeta potential. DODMA is extremely effective at encapsulating nucleic acids due to its ability to temporarily reduce pH.
Zhou Chen, Aili Zhang, Zhaogang Yang, Xinmei Wang, Lingqian Chang, Zhaofeng Chen and Ly James Lee, “Application of DODMA and Derivatives in Cationic Nanocarriers for Gene Delivery”, Current Organic Chemistry (2016) 20: 1813. https://doi.org/10.2174/138527...
C41H81NO2
C 79.41% H 13.17% N 2.26% O 5.16%
CAS Registry Number is a Registered Trademark of the American Chemical Society
Patel S, Ryals RC, Weller KK, Pennesi ME, Sahay G. Lipid nanoparticles for delivery of messenger RNA to the back of the eye. J Control Release. 2019 Apr 12;303:91-100. doi: 10.1016/j.jconrel.2019.04.015. [Epub ahead of print]
PubMed ID: 30986436- Certificate of Analysis (Lot No. 890899C-500MG-A-010 and 6539CPA010)
- Certificate of Analysis (Lot No. 890899C-100MG-A-010 and 6539CLA010)
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- Certificate of Analysis (Lot No. 890899C-500MG-B-011 and 6539CPB011)
- Certificate of Analysis (Lot No. 890899C-500MG-C-011 and 6539CPC011)
- Certificate of Analysis (Lot No. 890899C-100MG-A-011 and 6539CLA011)
- Certificate of Analysis (Lot No. 890899C-500MG-A-012 and 6539CPA012)
- Certificate of Analysis (Lot No. 890899C-100MG-A-012 and 6539CLA012)
- Certificate of Analysis (Lot No. 890899C-500MG-B-012 and 6539CPB012)
- Certificate of Analysis (Lot No. 890899C-500MG-C-012 and 6539CPC012)
- Certificate of Analysis (Lot No. 890899C-100MG-A-013 and 6539CLA013)
- Certificate of Analysis (Lot No. 890899C-500MG-A-013 and 6539CPA013)
- Certificate of Analysis (Lot No. 890899C-100MG-B-013 and 6539CLB013)
- Certificate of Analysis (Lot No. 890899C-500MG-B-013 and 6539CPB013)
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- Certificate of Analysis (Lot No. 890899C-500MG-C-013 and 6539CPC013)
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- Certificate of Analysis (Lot No. 890899C-500MG-A-014 and 6539CPA014)
- Certificate of Analysis (Lot No. 890899P-100MG-A-013 and 6539PLA013)
- Certificate of Analysis (Lot No. 890899P-500MG-A-014 and 6539PPA014)
- Certificate of Analysis (Lot No. 890899C-100MG-A-014 and 6539CLA014)