870341 | 18:1 PE (DOPE) pSar25
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-polysarcosine-25 (ammonium salt)
18:1 PE (DOPE) pSar25
1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-polysarcosine-25 (ammonium salt)
Polymers are a common modification made to lipids used for liposomal and lipid nanoparticle delivery systems. Adding a polymer-conjugated lipid to a formulation can improve several properties of the drug delivery system. Polyethyleneglycol (PEG) has historically been the most common polymer used in clinical practice. But recent studies have shown polysarcosine polymer-conjugated lipids to have similar stealth properties as PEG-conjugated lipids, but with the added bonus of an improved safety profile. Use 18:1 PE (DOPE) pSar25 as an alternative to 18:1 PE (DOPE) PEG2000 in your lipid formulations research today!
The molecular weight and exact mass are averages based on the polydispersity of PEG.
Polysarcosine-liposome formulations for mRNA delivery targeting the brain
C130H231N28O35P
C 56.22%, H 8.38%, N 14.12%, O 20.16%, P 1.12%
CAS Registry Number is a Registered Trademark of the American Chemical Society
- Certificate of Analysis (Lot No. 870341P-25MG-A-010 and 7102PJA010)
- Certificate of Analysis (Lot No. 870341P-25MG-B-010 and 7102PJB010)