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Polymers & Polymerizable Lipids

Polymerizable lipids & functional polymers for advanced formulation research.

Avanti Research provides a curated selection of polymerizable lipids and functional polymers to support advanced research in lipid-based delivery systems, membrane modeling, and biomedical formulations. These innovative lipid materials contain reactive groups designed for crosslinking, polymerization, and membrane anchoring.

With precise structural control and chemical reactivity, these functionalized lipids allow researchers to develop stable lipid nanoparticle (LNP) formulations, responsible delivery platforms, and synthetic membrane systems. Whether you're working on lipid polymers for nanomedicine or creating custom LNPs for gene therapy, our polymerizable lipids provide versatility and performance for your next breakthrough.

Drive biomedical research with stable, multifunctional polymerizable lipids.

Polymerizable lipids and functional polymers are foundational to innovations in lipid-based drug delivery systems, particularly for their role in creating stable, responsive, and tunable membranes. In LNP formulation, they enhance the mechanical integrity of vesicles while also enabling controlled drug delivery and programmable release profiles.

These polymer-functionalized lipids also improve membrane dynamics and stability, making them most suitable for high-stress environments like freeze-drying, thermal cycling, or systemic circulation. Reactive groups work as anchors for targeting ligands, antibodies, or imaging agents, paving the way for multifunctional delivery systems.

Additionally, photo- or thermo-crosslinkable membranes extend utility in optically responsive or temperature-triggered therapeutic platforms. Whether stabilizing liposomes or enabling precision diagnostics, these lipids are essential tools in translational medicine.

Boost lipid nanoparticle stability, targeting, and performance for advanced gene delivery.

When it comes to next-generation delivery systems, polymerizable lipids enhance LNP performance by reinforcing vesicle structure, improving circulation half-life, and enabling targeted tissue delivery. These lipid polymers are central to the success of mRNA and siRNA delivery platforms, which is demonstrated in the rapid development of mRNA vaccines.

Common reactive groups include:

Diacetylenes: Enabling photopolymerization for structural integrity
Methacrylates & Acrylates: Allowing UV-curing and hydrogel encapsulation
Thiols: Suitable for click chemistry and disulfide exchange.

Crosslinked membranes minimize content leaking, extend shelf life, and optimize release kinetics, making them invaluable for advanced LNP design in gene therapy.

Enable targeted delivery and compatibility with lipid systems.

Our polymerizable lipid catalog includes monomers and amphiphilic polymers that integrate seamlessly into existing lipid formulations. Compatible with phospholipids, PEG-lipids, and cationic lipids, they provide flexibility for traditional liposome systems and hybrid lipid-polymer nanoparticles.

Reactive side chains support site-specific conjugation to target ligands, fluorescent tags, or peptides, enabling real-time imaging and delivery guided by biomarkers.

If you need something specific, we can provide a custom synthesis and formulation consultation to ensure your lipids meet the precise performance and regulatory needs you require.

Ensure compliance with our fully documented polymerizable lipids.

All Avanti Research polymerizable lipids and polymers are rigorously tested to fulfill the highest standards of reproducibility and regulatory compliance. Every compound is delivered with detailed documentation to support regulatory submission or publication and is backed by:

A Certificate of Analysis (CoA)
A Material Safety Data Sheet (MSDS)
Batch traceability
Technical support for formulation consultation

In addition, the Avanti Research Quality Management System is NSF-ISR-certified.

Explore our polymerizable lipids and functionalized polymer products.

For formulation guidance or custom synthesis requests,contact our scientific team for expert support.