793042 | Di 18:0-N-pSar45—Tetrazine

Di 18:0-N-pSar45—Tetrazine

Di 18:0-N-pSar45—Tetrazine

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5mg 793042P-5mg 793042P-5mg 1 x 5mg $265.00
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Di 18:0-N-pSar45—Tetrazine

Di 18:0-N-pSar45—Tetrazine

Polysarcosine (pSar) lipids are offered as alternatives to traditional PEGylated lipids used in RNA delivery vehicles. Compared to similar PEGylated lipid nanoparticles (LNPs), pSar LNPs have shown improved mRNA transfection potency and improved safety profiles.

Di 18:0-N-pSar-Tetrazine is a polysarcosine-lipid conjugate that is being studied for its use within drug delivery systems as an alternative to traditional PEGylation in LNPs. The tetrazine moiety allows the molecule to be used in biorthogonal click chemistry. Tetrazine reacts specifically with trans-cyclooctene (TCO) and can occur in complex biological environments without interfering with other biological processes.
Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C181H306N50O46
Purity
>99%
Stability
1 year
Storage Temperature
-20°C
Formula Weight
3918.74
Exact Mass
3916.31

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