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850105 | 20:4 Lyso PI

1-arachidonoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt)

20:4 Lyso PI

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500µg 850105P-500ug 850105P-500ug $850.00
100µg 850105P-100ug 850105P-100ug $213.00
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Info

20:4 Lyso PI

1-arachidonoyl-2-hydroxy-sn-glycero-3-phosphoinositol (ammonium salt)

Increased circulating levels of L-alpha-lysophosphatidylinositol (LPI) are associated with cancer and LPI is a potent ligand for the G-protein-coupled receptor GPR55.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C29H52NO12P
Percent Composition
C 54.62%, H 8.22%, N 2.20%, O 30.11%, P 4.86%
Purity
>99% LPI; may contain up to 10% of the 2-LPI isomer
Stability
3 Months
Storage Temperature
-20°C
CAS Number
1246430-04-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
637.696
Exact Mass
637.323
Synonyms
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-2-hydroxy-sn-glycero-3-phospho-(1'-myo-inositol) (ammonium salt)
PI(20:4(5Z,8Z,11Z,14Z)/0:0)
Solubility in Different Solvents
Soluble in ethanol, DMSO, and Chloroform:Methanol:Water (65:25:4) at 5mg/mL
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References

Eum JY, Lee JC, Yi SS, Kim IY, Seong JK, Moon MH. Aging-related lipidomic changes in mouse serum, kidney, and heart by nanoflow ultrahigh-performance liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2020 Jan 3:460849. doi: 10.1016/j.chroma.2020.460849. Epub ahead of print. PMID: 31928769.

 PubMed ID: 31928769

Guy AT, Kano K, Ohyama J, Kamiguchi H, Hirabayashi Y, Ito Y, Matsuo I, Greimel P. Preference for Glucose over Inositol Headgroup during Lysolipid Activation of G Protein-Coupled Receptor 55. ACS Chem Neurosci. 2018 Oct 29. doi: 10.1021/acschemneuro.8b00505. [Epub ahead of print]
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