840033 | 14:0 PS

1,2-dimyristoyl-sn-glycero-3-phospho-L-serine (sodium salt)

14:0 PS

Powder

Size SKU Packaging Price
10mg 840033P-10mg 840033P-10mg 1 x 10mg $117.10
25mg 840033P-25mg 840033P-25mg 1 x 25mg $163.50
200mg 840033P-200mg 840033P-200mg 1 x 200mg $908.00
Request Bulk Pricing

Info

14:0 PS

1,2-dimyristoyl-sn-glycero-3-phospho-L-serine (sodium salt)

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C34H65NO10PNa
Percent Composition
C 58.19%, H 9.33%, N 2.00%, Na 3.28%, O 22.80%, P 4.41%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
105405-50-3
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
701.844
Exact Mass
701.424
Synonyms
1,2-ditetradecanoyl-sn-glycero-3-phospho-L-serine (sodium salt)
DMPS
PS(14:0/14:0)
Transition Temp
35°C
Solubility in Different Solvents
Insoluble in ethanol and DMSO, soluble in Chloroform:Methanol:Water (65:25:4) at 5mg/mL
References

Adão R, Cruz PF, Vaz DC, Fonseca F, Pedersen JN, Ferreira-da-Silva F, Brito RMM, Ramos CHI, Otzen D, Keller S, Bastos M. DIBMA nanodiscs keep α-synuclein folded. Biochim Biophys Acta Biomembr. 2020 Apr 15;1862(9):183314. doi: 10.1016/j.bbamem.2020.183314. Epub ahead of print. PMID: 32304757.

PubMed ID: 32304757

Huang P, Huang CY, Lin TC, Lin LE, Yang E, Lee C, Hsu CC, Chou PT. Toward the Rational Design of Universal Dual Polarity Matrix for MALDI Mass Spectrometry. Anal Chem. 2020 May 19;92(10):7139-7145. doi: 10.1021/acs.analchem.0c00570. Epub 2020 May 4. PMID: 32314914.

PubMed ID: 32314914

Bryce DA, Kitt JP, Myres GJ, Harris JM. Confocal Raman Microscopy Investigation of Phospholipid Monolayers Deposited on Nitrile-Modified Surfaces in Porous Silica Particles. Langmuir. 2020 Apr 21;36(15):4071-4079. doi: 10.1021/acs.langmuir.0c00456. Epub 2020 Apr 7. PMID: 32212663.

PubMed ID: 32212663

da Costa E, Ricardo F, Melo T, Mamede R, Abreu MH, Domingues P, Domingues MR, Calado R. Site-Specific Lipidomic Signatures of Sea Lettuce (Ulva spp., Chlorophyta) Hold the Potential to Trace Their Geographic Origin. Biomolecules. 2020 Mar 23;10(3):E489. doi: 10.3390/biom10030489. PMID: 32210093.

PubMed ID: 32210093

Santa-Marinha L, Castanho I, Silva RR, Bravo FV, Miranda AM, Meira T, Morais-Ribeiro R, Marques F, Xu Y, Point du Jour K, Wenk M, Chan RB, Di Paolo G, Pinto V, Oliveira TG. Phospholipase D1 Ablation Disrupts Mouse Longitudinal Hippocampal Axis Organization and Functioning. Cell Rep. 2020 Mar 24;30(12):4197-4208.e6. doi: 10.1016/j.celrep.2020.02.102. PMID: 32209478.

PubMed ID: 32209478

Bryce DA, Kitt JP, Myres GJ, Harris JM. Confocal Raman Microscopy Investigation of Phospholipid Monolayers Deposited on Nitrile-Modified Surfaces in Porous Silica Particles. Langmuir. 2020 Apr 7. doi: 10.1021/acs.langmuir.0c00456. Epub ahead of print. PMID: 32212663.

PubMed ID: 32212663

DeLisle CF, Malooley AL, Banerjee I, Lorieau JL. Pro-islet amyloid polypeptide in micelles contains a helical prohormone segment. FEBS J. 2020 Feb 19. doi: 10.1111/febs.15253. Epub ahead of print. PMID: 32077246.

PubMed ID: 32077246

Peterka O, Jirásko R, Chocholoušková M, Kuchař L, Wolrab D, Hájek R, Vrána D, Strouhal O, Melichar B, Holčapek M. Lipidomic characterization of exosomes isolated from human plasma using various mass spectrometry techniques. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jan 21;1865(5):158634. doi: 10.1016/j.bbalip.2020.158634. Epub ahead of print. PMID: 31978556.

PubMed ID: 31978556

Suchodolski J, Muraszko J, Korba A, Bernat P, Krasowska A. Lipid composition and cell surface hydrophobicity of Candida albicans influence the efficacy of fluconazole-gentamicin treatment. Yeast. 2020 Jan;37(1):117-129. doi: 10.1002/yea.3455. Epub 2020 Jan 10. PMID: 31826306.

PubMed ID: 31826306

Mias-Lucquin D, Dos Santos Morais R, Chéron A, Lagarrigue M, Winder SJ, Chenuel T, Pérez J, Appavou MS, Martel A, Alviset G, Le Rumeur E, Combet S, Hubert JF, Delalande O. How the central domain of dystrophin acts to bridge F-actin to sarcolemmal lipids. J Struct Biol. 2020 Jan 1;209(1):107411. doi: 10.1016/j.jsb.2019.107411. Epub 2019 Nov 2. PMID: 31689503.

PubMed ID: 31689503

Li H, Song Y, Zhang H, Wang X, Cong P, Xu J, Xue C. Comparative lipid profile of four edible shellfishes by UPLC-Triple TOF-MS/MS. Food Chem. 2020 Apr 25;310:125947. doi: 10.1016/j.foodchem.2019.125947. Epub 2019 Dec 4. PMID: 31841939.

PubMed ID: 31841939

Gill EL, Koelmel JP, Meke L, Yost RA, Garrett TJ, Okun MS, Flores C, Vedam-Mai V. Ultrahigh-Performance Liquid Chromatography-High-Resolution Mass Spectrometry Metabolomics and Lipidomics Study of Stool from Transgenic Parkinson's Disease Mice Following Immunotherapy. J Proteome Res. 2020 Jan 3;19(1):424-431. doi: 10.1021/acs.jproteome.9b00605. Epub 2019 Nov 22.

PubMed ID: 31713431

Perczyk P, Wójcik A, Wydro P, Broniatowski M. The role of phospholipid composition and ergosterol presence in the adaptation of fungal membranes to harsh environmental conditions-membrane modeling study. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183136. doi: 10.1016/j.bbamem.2019.183136. Epub 2019 Nov 18.

PubMed ID: 31751523

Chamberlain CA, Hatch M, Garrett TJ. Metabolomic profiling of oxalate-degrading probiotic Lactobacillus acidophilus and Lactobacillus gasseri. PLoS One. 2019 Sep 23;14(9):e0222393. doi: 10.1371/journal.pone.0222393. eCollection 2019.

PubMed ID: 31545840

Lopes D, Melo T, Meneses J, Abreu MH, Pereira R, Domingues P, Lillebø AI, Calado R5, Domingues MR. A New Look for the Red Macroalga Palmaria palmata: A Seafood with Polar Lipids Rich in EPA and with Antioxidant Properties. Mar Drugs. 2019 Sep 13;17(9). pii: E533. doi: 10.3390/md17090533.

PubMed ID: 31540326

Bose D, Chakrabarti A. Chaperone potential of erythroid spectrin: Effects of hemoglobin interaction, macromolecular crowders, phosphorylation and glycation. Biochim Biophys Acta Proteins Proteom. 2019 Nov;1867(11):140267. doi: 10.1016/j.bbapap.2019.140267. Epub 2019 Aug 27.

PubMed ID: 31470132

Wang X, Zhang H, Song Y, Cong P, Li Z, Xu J, Xue C. Comparative Lipid Profile Analysis of Four Fish Species by Ultraperformance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry. J Agric Food Chem. 2019 Aug 21;67(33):9423-9431. doi: 10.1021/acs.jafc.9b03303. Epub 2019 Aug 8.

PubMed ID: 31329442

Chung KP, Hsu CL, Fan LC, Huang Z, Bhatia D, Chen YJ, Hisata S, Cho SJ, Nakahira K, Imamura M, Choi ME, Yu CJ, Cloonan SM, Choi AMK. Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis. Nat Commun. 2019 Jul 29;10(1):3390. doi: 10.1038/s41467-019-11327-1.

PubMed ID: 31358769

Zhou H, Lei X, Yan Y, Lydic T, Li J, Weintraub NL, Su H, Chen W. Targeting ATGL to rescue BSCL2 lipodystrophy and its associated cardiomyopathy. JCI Insight. 2019 Jun 11;5. pii: 129781. doi: 10.1172/jci.insight.129781.

PubMed ID: 31185001

Gryz E, Perlińska-Lenart U, Gawarecka K, Jozwiak A, Piłsyk S, Lipko A, Jemiola-Rzeminska M, Bernat P, Muszewska A, Steczkiewicz K, Ginalski K, Długoński J, Strzalka K, Swiezewska E, Kruszewska JS. Poly-Saturated Dolichols from Filamentous Fungi Modulate Activity of Dolichol-Dependent Glycosyltransferase and Physical Properties of Membranes. Int J Mol Sci. 2019 Jun 21;20(12). pii: E3043. doi: 10.3390/ijms20123043.

PubMed ID: 31234450

Holopainen M, Colas RA, Valkonen S, Tigistu-Sahle F, Hyvärinen K, Mazzacuva F, Lehenkari P, Käkelä R, Dalli J, Kerkelä E, Laitinen S. Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Jun 15;1864(10):1350-1362. doi: 10.1016/j.bbalip.2019.06.010. [Epub ahead of print]

PubMed ID: 31207356

Shuddhodana, Zaher Judeh. Alginate-coating of artemisinin-loaded cochleates results in better control over gastro-intestinal release for effective oral delivery. Journal of Drug Delivery Science and Technology. August 2019;52:27-36. doi: 10.1016/j.jddst.2019.04.020


Dalchand N, Doğangün M, Ohno PE, Ma E, Martinson ABF, Geiger FM. Perturbation of Hydrogen Bonding Networks Over Supported Lipid Bilayers by Poly (allylamine hydrochloride). J Phys Chem B. 2019 Apr 23. doi: 10.1021/acs.jpcb.9b02392. [Epub ahead of print]

PubMed ID: 31013086

Bender BJ, Vortmeier G, Ernicke S, Bosse M, Kaiser A, Els-Heindl S, Krug U, Beck-Sickinger A, Meiler J, Huster D. Structural Model of Ghrelin Bound to its G Protein-Coupled Receptor. Structure. 2019 Mar 5;27(3):537-544.e4. doi: 10.1016/j.str.2018.12.004. Epub 2019 Jan 24.

PubMed ID: 30686667

Carija A, Pinheiro F, Pujols J, Brás IC, Lázaro DF, Santambrogio C, Grandori R, Outeiro TF, Navarro S, Ventura S. Biasing the native α-synuclein conformational ensemble towards compact states abolishes aggregation and neurotoxicity. Redox Biol. 2019 Apr;22:101135. doi: 10.1016/j.redox.2019.101135. Epub 2019 Feb 5.

PubMed ID: 30769283

Shue Li, Hongbo Yu, Yuxin Liu, Xiaoyu Zhang, Fuying Ma. The lipid strategies in Cunninghamella echinulata for an allostatic response to temperature changes. Process Biochemistry. 2019 January;76:85-94. doi: 10.1016/j.procbio.2018.11.005


Suga K, Lai YC, Faried M, Umakoshi H. Direct Observation of Amyloid β Behavior at Phospholipid Membrane Constructed on Gold Nanoparticles. Int J Anal Chem. 2018 Dec 2;2018:2571808. doi: 10.1155/2018/2571808. eCollection 2018.

PubMed ID: 30627164

Wang W, Xin J, Yang X, Lam SM, Shui G, Wang Y, Huang X. Lipid-gene regulatory network reveals coregulations of triacylglycerol with phosphatidylinositol/lysophosphatidylinositol and with hexosyl-ceramide. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Feb;1864(2):168-180. doi: 10.1016/j.bbalip.2018.11.010. Epub 2018 Dec 3.

PubMed ID: 30521938

Kot EF, Arseniev AS, Mineev KS. On the behavior of most widely spread lipids in isotropic bicelles. Langmuir. 2018 Jun 20. doi: 10.1021/acs.langmuir.8b01454. [Epub ahead of print]

PubMed ID: 29924628

Fichtl B, Silman I, Schneider MF. On the Physical Basis of Biological Signaling by Interface Pulses. Langmuir. 2018 Apr 11. doi: 10.1021/acs.langmuir.7b01613.

PubMed ID: 29613802

Laursen, T., Borch, J., Knudsen, C., Torta, F., Martens, H.J., SIvestro, D., Hatzakis, N.S., Wenk, M.R., Dafforn, T.R., Olsen, C.E., Motawia, M.S., Hamberger, B., Moller, B.L., and Bassard, J-E. “Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum” Science 354, 890-893 (2016)

PubMed ID: 27856908

F. Schmidt, Line Cantin, Kristina Klinker and Christian Salesse. Phosphatidylserine Allows Observation of the Calcium–Myristoyl Switch of Recoverin and Its Preferential Binding Philippe Calvez, Thaís J. Am. Chem. Soc., Article ASAP Publication Date (Web): October 11, 2016 [PubMed]

PubMed ID: 27689444

Leventis, P.A., Grinstein, S. (2010) The distribution and function of phosphatidylserine in cellular membranes. Annu Rev Biophys. 39:407-27. Review. [PubMed]

PubMed ID: 20192774

André Hädicke, Christian Schwieger, and Alfred Blume. Co-spreading of anionic phospholipids with peptides of the structure (KX)4K at the air-water interface: Influence of lipid headgroup structure and hydrophobicity of the peptide on monolayer behavior. Langmuir, Just Accepted Manuscript


Bicelle Preparation

Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Reference/Protocol

Certificates of Analysis

Related Products

Cart

Item Price Qty.
${ item.sku }
Base Price: $${ (item.price - (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150))).toFixed(2) }
Custom Packaging: +${ (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150)).toFixed(2) }

Change Custom Packaging
$ ${ item.total.toFixed(2) }
Subtotal: ${ cart.itemSubtotal|money }
${ adjustment.name } ${ adjustment.amountAsCurrency }
Order Total: ${ cart.totalPriceAsCurrency }