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810270 | C11 TopFluor™ Ceramide-1-Phosphate

N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-erythro-sphingosine-1-phosphate (ammonium salt)

C11 TopFluor™ Ceramide-1-Phosphate

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C11 TopFluor™ Ceramide-1-Phosphate

N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-erythro-sphingosine-1-phosphate (ammonium salt)

Ceramide-1-phosphate is well known as a second messenger and an important mediator of inflammatory response. The availability of this new fluorescent metabolite provides the researcher with new ways to track cell migration and G protein coupled activity.

Data
Hygroscopic
Yes
Light Sensitive
Yes
Molecular Formula
C42H74BF2N4O6P
Percent Composition
C 62.21%, H 9.20%, B 1.33%, F 4.69%, N 6.91%, O 11.84%, P 3.82%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
2260795-50-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
810.842
Exact Mass
810.541
Synonyms
N-[11-(TopFluor)undecanoyl]-D-ceramide-1-phosphate (ammonium salt)
Ex/Em
496/511nm
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References

Kuc N, Doermann A, Shirey C, Lee DD, Lowe CW, Awasthi N, Schwarz RE, Stahelin RV, Schwarz MA. Pancreatic ductal adenocarcinoma cell secreted extracellular vesicles containing ceramide-1-phosphate promote pancreatic cancer stem cell motility. Biochem Pharmacol. 2018 Oct;156:458-466. doi: 10.1016/j.bcp.2018.09.017. Epub 2018 Sep 15. PMID: 30222969; PMCID: PMC6207932.

 PubMed ID: 30222969

Shirey CM, Ward KE, Stahelin RV. Investigation of the biophysical properties of a fluorescently modified ceramide-1-phosphate. Chem Phys Lipids. 2016 Oct;200:32-41. doi: 10.1016/j.chemphyslip.2016.06.004. Epub 2016 Jun 16. PMID: 27318040; PMCID: PMC5159338.

 PubMed ID: 27318040
Certificates of Analysis

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