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750332 | 14:0 Cardiolipin (sodium salt)

1',3'-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (sodium salt)

14:0 Cardiolipin (sodium salt)

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Size SKU Packaging Price
25mg 750332P-25mg 750332P-25mg 1 x 25mg $135.50
200mg 750332P-200mg 750332P-200mg 1 x 200mg $466.00
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Chloroform

Size SKU Packaging Price
25mg 750332C-25mg 750332C-25mg 1 x 25mg 10mg/mL 2.5mL $135.50 135.5
200mg 750332C-200mg 750332C-200mg 2 x 100mg 25mg/mL 4mL $466.00 466
Request Bulk Pricing
Info

14:0 Cardiolipin (sodium salt)

1',3'-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (sodium salt)

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C65H124Na2O17P2
Percent Composition
C 60.73%, H 9.72%, Na 3.58%, O 21.16%, P 4.82%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
63988-21-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
1285.597
Exact Mass
1284.811
Synonyms
1,1',2,2'-tetratetradecanoyl cardiolipin (sodium salt)
CL(1'-[14:0/14:0],3'-[14:0/14:0])
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References

Shon JC, Lee SM, Jung JH, Wu Z, Kwon YS, Sim HJ, Seo JS. Integrated metabolomics and lipidomics reveals high accumulation of polyunsaturated lysoglycerophospholipids in human lung fibroblasts exposed to fine particulate matter. Ecotoxicol Environ Saf. 2020 Jul 1;202:110896. doi: 10.1016/j.ecoenv.2020.110896. Epub ahead of print. PMID: 32622306.

 PubMed ID: 32622306

Juhaniewicz-Debinska J, Dziubak D, Sek S. Physicochemical Characterization of Daptomycin Interaction with Negatively Charged Lipid Membranes. Langmuir. 2020 Apr 27. doi: 10.1021/acs.langmuir.0c00716. Epub ahead of print. PMID: 32340456.

 PubMed ID: 32340456

Perczyk P, Wójcik A, Hachlica N, Wydro P, Broniatowski M. The composition of phospholipid model bacterial membranes determines their endurance to secretory phospholipase A2 attack - The role of cardiolipin. Biochim Biophys Acta Biomembr. 2020 Feb 28;1862(6):183239. doi: 10.1016/j.bbamem.2020.183239. Epub ahead of print. PMID: 32119861.

 PubMed ID: 32119861

Sun Y, Saito K, Saito Y. Lipid Profile Characterization and Lipoprotein Comparison of Extracellular Vesicles from Human Plasma and Serum. Metabolites. 2019 Nov 1;9(11). pii: E259. doi: 10.3390/metabo9110259.

 PubMed ID: 31683897

Malik E, Phoenix DA, Badiani K, Snape TJ, Harris F, Singh J, Morton LHG, Dennison SR. Biophysical studies on the antimicrobial activity of linearized esculentin 2EM. Biochim Biophys Acta Biomembr. 2020 Feb 1;1862(2):183141. doi: 10.1016/j.bbamem.2019.183141. Epub 2019 Nov 29.

 PubMed ID: 31790693

Li N, Wang P, Liu X, Han C, Ren W, Li T, Li X, Tao F, Zhao Z. Developing IR-780 as a Novel Matrix for Enhanced MALDI MS Imaging of Endogenous High-Molecular-Weight Lipids in Brain Tissues. Anal Chem. 2019 Dec 17;91(24):15873-15882. doi: 10.1021/acs.analchem.9b04315. Epub 2019 Nov 26.

 PubMed ID: 31718156

Pizzuto M, Lonez C, Baroja-Mazo A, Martínez-Banaclocha H, Tourlomousis P, Gangloff M, Pelegrin P, Ruysschaert JM, Gay NJ, Bryant CE. Saturation of acyl chains converts cardiolipin from an antagonist to an activator of Toll-like receptor-4. Cell Mol Life Sci. 2019 Sep;76(18):3667-3678. doi: 10.1007/s00018-019-03113-5. Epub 2019 May 6.

 PubMed ID: 31062071

Beata Sadowska, Dariusz Laskowski, Przemysław Bernat, Bartłomiej Micota, Marzena Wieckowska-Szakiel, Anna Podsedek, and Barbara Rózalska. Molecular Mechanisms of Leonurus Cardiaca L. Extract Activity in Prevention of Staphylococcal Endocarditis—Study on in Vitro and ex Vivo Models. Molecules 2019, 24, 3318; doi:10.3390/molecules24183318

Lopes D, Melo T, Meneses J, Abreu MH, Pereira R, Domingues P, Lillebø AI, Calado R, Domingues MR. A New Look for the Red Macroalga Palmaria palmata: A Seafood with Polar Lipids Rich in EPA and with Antioxidant Properties. Mar Drugs. 2019 Sep 13;17(9). pii: E533. doi: 10.3390/md17090533.

 PubMed ID: 31540326

Li M, Mandal A, Tyurin VA, DeLucia M, Ahn J, Kagan VE, van der Wel PCA. Surface-Binding to Cardiolipin Nanodomains Triggers Cytochrome c Pro-apoptotic Peroxidase Activity via Localized Dynamics. Structure. 2019 Mar 4. pii: S0969-2126(19)30051-6. doi: 10.1016/j.str.2019.02.007. [Epub ahead of print]

 PubMed ID: 30879887

Krebs SJ, Kwon YD, Schramm CA, Law WH, Donofrio G, Zhou KH, Gift S, Dussupt V, Georgiev IS, Schätzle S, McDaniel JR, Lai YT, Sastry M, Zhang B, Jarosinski MC, Ransier A, Chenine AL, Asokan M, Bailer RT, Bose M, Cagigi A, Cale EM, Chuang GY, Darko S, Driscoll JI, Druz A, Gorman J, Laboune F, Louder MK, McKee K, Mendez L, Moody MA, O'Sullivan AM, Owen C, Peng D, Rawi R, Sanders-Buell E, Shen CH, Shiakolas AR, Stephens T, Tsybovsky Y, Tucker C, Verardi R, Wang K, Zhou J, Zhou T, Georgiou G, Alam SM, Haynes BF, Rolland M, Matyas GR, Polonis VR, McDermott AB, Douek DC, Shapiro L, Tovanabutra S, Michael NL, Mascola JR, Robb ML, Kwong PD, Doria-Rose NA. Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity. 2019 Mar 19;50(3):677-691.e13. doi: 10.1016/j.immuni.2019.02.008. Epub 2019 Mar 12.

 PubMed ID: 30876875

Barbosa SC, Nobre TM, Volpati D, Cilli EM, Correa DS, Oliveira ON Jr. The cyclic peptide labaditin does not alter the outer membrane integrity of Salmonella enterica serovar Typhimurium. Sci Rep. 2019 Feb 13;9(1):1993. doi: 10.1038/s41598-019-38551-5.

 PubMed ID: 30760803

Wojcik A, Pawlowski M, Wydro P, Broniatowski M. Effects of Polychlorinated Pesticides and Their Metabolites on Phospholipid Organization in Model Microbial Membranes. J Phys Chem B. 2018 Nov 29. doi: 10.1021/acs.jpcb.8b08989. [Epub ahead of print].

 PubMed ID: 30497266

Kensbock R, Ahrens H, Helm CA. Interactions of Monovalent and Divalent Cations with Cardiolipin Monolayers. Langmuir. 2019 Feb 25. doi: 10.1021/acs.langmuir.8b03637. [Epub ahead of print]

 PubMed ID: 30732452

Muenzner, J., J.R. Toffey, Y. Hong, and E.V. Pletneva. (2013). Becoming a Peroxidase: Cardiolipin-Induced Unfolding of Cytochrome c. J Phys Chem B [PubMed]

 PubMed ID: 23713573

André Hädicke, Christian Schwieger, and Alfred Blume. Co-spreading of anionic phospholipids with peptides of the structure (KX)4K at the air-water interface: Influence of lipid headgroup structure and hydrophobicity of the peptide on monolayer behavior. Langmuir, Just Accepted Manuscript [PubMed]
Certificates of Analysis

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