Lipopeptides
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Avanti Research™ offers a highly selective range of synthetic lipopeptides designed to support immune system research, vaccine development, and targeted delivery systems. These lipidated peptides, formed by covalently linking lipid tails to short peptide sequences, play an important role in modulating immune responses. Thanks to their amphiphilic nature, lipopeptides can engage Toll-like receptors (TLRs) and integrate into lipid membranes, making them indispensable in preclinical immunology and peptide-based vaccine development.
Our research-grade lipopeptides are engineered for optimal purity and functional consistency to offer researchers reliable tools for studying innate immune signaling, improving antigen presentation, and developing self-adjuvanting vaccine platforms.
Advance your immunology and therapeutics groundwork with cutting-edge lipopeptides.
Lipopeptides serve as potent immunostimulants and are frequently used as adjuvants in experimental and preclinical vaccines to improve innate and adaptive immune responses. Their molecular structure allows them to mimic bacterial lipoproteins and trigger TLRs, particularly TLR2/1 and TLR2/6 pathways.
Interest in these molecules is quickly growing in immunological research for their ability to modulate immune signaling, promote antigen-presenting cell activation, and support the development of self-adjuvanting peptide vaccines. Their lipid-peptide architecture can be customized to improve delivery efficiency, receptor specificity, or immunogenic response, which are all essential for advancing vaccine and immunotherapy platforms
Additionally, their amphiphilic architecture enables their integration into membranes or liposomal delivery systems to enhance their cellular uptake and target in drug delivery or membrane fusion models. Lipopeptides are also applied in diagnostic assays, where their immune-activating characteristics detect immune response anomalies or study receptor-specific interactions.
See what our research-grade lipopeptides can do.
Our synthetic lipopeptides are produced to the highest scientific standards:
High purity and stability: Each lipopeptide is synthesized using precision-controlled chemistry to ensure high chemical purity and batch-to-batch reproducibility.
Research-ready quantities: Compounds are available in standardized research quantities, ideal for early-stage studies and method development.
Validated for immune applications: Designed and tested for use in TLR activation, peptide-lipid conjugation, and vaccine delivery systems.
Custom synthesis options: Custom-tailored options are available, including lipid tail variation, linker design, and peptide sequence customization to meet specific research objectives.
Achieve credible research results thanks to detailed documentation and scientific integrity.
All Avanti Research™ lipopeptides are rigorously tested to fulfill the highest standards of reproducibility and regulatory compliance. Every compound is delivered with detailed documentation to support regulatory submission or publication and is backed by:
A Certificate of Analysis (CoA)
A Material Safety Data Sheet (MSDS)
Batch traceability
Technical support for formulation consultation
In addition, the Avanti Research Quality Management System is NSF-ISR-certified.
Frequently asked questions.
What are lipopeptides used for in vaccine research?
Lipopeptides are used as immunostimulatory adjuvants in vaccine formulations. They enhance immune responses by activating Toll-like receptors, especially TLR2, and are often used to design self-adjuvanting peptide vaccines.
Do you provide custom lipopeptide synthesis?
Yes, we offer custom synthesis services for researchers in need of tailored lipid tails, peptide sequences, or conjugation chemistries. Contact us to discuss your project's specifications!
What documentation is included with your compounds?
Each product comes with a Certificate of Analysis (CoA) and Material Safety Data Sheet (MSDS). Additional information, such as formulation guidance, is available upon request.