Acyl Carnitine Lipids
Acylcarnitines are acyl esters of the quaternary ammonium compound carnitine. These esters are essential for the catabolism of fatty acids and maintenance of energy homeostasis in the human body. Acylcarnitines transport acyl groups from fatty acids into the mitochondria to generate energy. These molecules are capable of moving through the mitochondrial and cell membranes via a carnitine shuttle. There are several disorders that have been linked to acylcarnitine metabolic defects including various acyl-CoA dehydrogenase deficiencies. These defects typically manifest as encephalopathy, cardiomyopathy, and myopathy. Milder acylcarnitine abnormalities have been detected in diseases such as insulin resistance, cardiovascular disease, and Alzheimer's disease.
https://www.lipidmaps.org/resources/lipidweb/lipidweb_html/lipids/simple/carnitin/index.htm
Gerald Liew, Benita Tse, I-Van Ho, Nichole Joachim, Andrew White, Russell Pickford, David Maltby, Bamini Gopinath, Paul Mitchell, Ben Crossett; Acylcarnitine Abnormalities Implicate Mitochondrial Dysfunction in Patients With Neovascular Age-Related Macular Degeneration. Invest. Ophthalmol. Vis. Sci. 2020;61(8):32. DOI: https://doi.org/10.1167/iovs.61.8.32.
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- BUY 870337 - C10:0 L-carnitine (HCl salt)
- BUY 870850 - C12 Carnitine
- BUY 870851 - C16 Carnitine
- BUY 870852 - C18:1(Δ9-cis) Carnitine
- BUY 870854 - C14 Carnitine (HCl salt)
- BUY 870855 - 3-Me-Glutaryl Carnitine
- BUY 870859 - C2:0 L-carnitine (HCl salt)
- BUY 870862 - C8:0 L-carnitine
- BUY 870863 - C16:0(alkyne) L-carnitine
- BUY 870864 - pacFA L-carnitine
- BUY 870866 - C5:0 L-carnitine (HCl salt)
- BUY 870867 - C14:1 L-carnitine (HCl salt)
- BUY 870869 - C15:0 L-carnitine (HCl salt)
- BUY 870870 - C4:0 L-carnitine (HCl salt)
- BUY 870871 - C12:1 L-carnitine (HCl salt)
- BUY 870873 - Adipoyl-L-carnitine
- BUY 870875 - Malonyl-L-carnitine