700123 | CholPC
cholesteryl phosphocholine

CholPC
cholesteryl phosphocholine
Ceramide forms stable, fluid bilayers with cholesteryl phosphocholine, and this formulation has been shown to be more potent than solvent-delivered (DMSO) formulations of C6 Ceramide in inhibiting proliferation, inducing apoptosis, and disturbing calcium homeostasis.
CholPC forms bilayers (giant uni- and multilamellar vesicles, as well as extruded large unilamellar vesicles) with both ceramides and cholesterol. The extruded bilayers appear to be fluid, although highly ordered, even when the ceramide has an N-linked palmitoyl acyl chain.
CAS Registry Number is a Registered Trademark of the American Chemical Society
Backman APE, Halin J, Kjellberg MA, Mattjus P. Indirect Lipid Transfer Protein Activity Measurements Using Quantification of Glycosphingolipid Production. Methods Mol Biol. 2019;1949:105-114. doi: 10.1007/978-1-4939-9136-5_9. PMID: 30790252.
PubMed ID: 30790252Sukumaran P, Lönnfors M, Långvik O, Pulli I, Törnquist K, Slotte JP. Complexation of c6-ceramide with cholesteryl phosphocholine - a potent solvent-free ceramide delivery formulation for cells in culture. PLoS One. 2013 Apr 19;8(4):e61290. doi: 10.1371/journal.pone.0061290. PMID: 23620740; PMCID: PMC3631171.
PubMed ID: 23620740Lönnfors M, Långvik O, Björkbom A, Slotte JP. Cholesteryl phosphocholine--a study on its interactions with ceramides and other membrane lipids. Langmuir. 2013 Feb 19;29(7):2319-29. doi: 10.1021/la3051324. Epub 2013 Feb 4. PMID: 23356741.
PubMed ID: 23356741- Certificate of Analysis (Lot No. 700123P-25MG-A-010 and 5192PJA010)
- Certificate of Analysis (Lot No. 700123P-500MG-A-010 and 5192PPA010)
- Certificate of Analysis (Lot No. 700123P-500MG-B-010 and 5192PPB010)
- Certificate of Analysis (Lot No. 700123P-25MG-B-010 and 5192PJB010)
- Certificate of Analysis (Lot No. 700123P-25MG-C-010 and 5192PJC010)
- Certificate of Analysis (Lot No. 700123P-25MG-D-010 and 5192PJD010)
- Certificate of Analysis (Lot No. 700123P-25MG-E-010 and 5192PJE010)