900410 | 5-PAHSA
5-(palmitoyloxy)octadecanoic acid
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5-PAHSA
5-(palmitoyloxy)octadecanoic acid
PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through GPR120 to enhance insulin-stimulated glucose uptake. Thus, FAHFAs are endogenous lipids with the potential to treat type 2 diabetes.
CAS Registry Number is a Registered Trademark of the American Chemical Society
Powered by BiozPham TH, Vidal NP, Manful CF, Fillier TA, Pumphrey RP, Doody KM, Thomas RH. Moose and Caribou as Novel Sources of Functional Lipids: Fatty Acid Esters of Hydroxy Fatty Acids, Diglycerides and Monoacetyldiglycerides. Molecules. 2019 Jan 10;24(2). pii: E232. doi: 10.3390/molecules24020232.
PubMed ID: 30634564Kolar, M.J., S.S. Kamat, W.H. Parsons, E.A. Homan, T. Maher, O.D. Peroni, I. Syed, K. Fjeld, A. Molven, B.B. Kahn, B.F. Cravatt, and A. Saghatelian. (2016). Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. Biochemistry 55:4636-41.
PubMed ID: 27509211Yore, M.M., I. Syed, P.M. Moraes-Vieira, T. Zhang, M.A. Herman, E.A. Homan, R.T. Patel, J. Lee, S. Chen, O.D. Peroni, A.S. Dhaneshwar, A. Hammarstedt, U. Smith, T.E. McGraw, A. Saghatelian, and B.B. Kahn. (2014). Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell 159:318-32.
PubMed ID: 25303528- Certificate of Analysis (Lot No. 900410C-1MG-A-010 and 6385CGA010)
- Certificate of Analysis (Lot No. 900410C-1MG-B-010 and 6385CGB010)
- Certificate of Analysis (Lot No. 900410C-1MG-C-010 and 6385CGC010)
- Certificate of Analysis (Lot No. 900410C-1MG-D-010 and 6385CGD010)
