Section Menu

890830 | 16:0 DAP

1,2-dipalmitoyl-3-dimethylammonium-propane

16:0 DAP

Powder

Size SKU Packaging Price
25mg 890830P-25mg 890830P-25mg 1 x 25mg $223.75
200mg 890830P-200mg 890830P-200mg 1 x 200mg $468.00
Request Bulk Pricing
Info

16:0 DAP

1,2-dipalmitoyl-3-dimethylammonium-propane

16:0 DAP, or 1,2-dipalmitoyl-3-dimethylammonium-propane, is a cationic lipid designed for research applications. A pH-sensitive transfection reagent, this lipid stands out for its versatility and reliability. It is often used to formulate lipid nanoparticles (LNPs) or for the transcription of miRNA in cancer research use. 16:0 DAP is what you need to achieve superior results in your scientific research.

Application

While it serves as a pH-sensitive reagent, 16:0 DAP is particularly effective in preparing miRNA-encapsulated liposomes, making it indispensable for researchers focused on gene delivery and transfection. Its pH-sensitive properties enable precise control and optimization in various experimental conditions, enhancing the efficiency of miRNA transcription, especially in oral cancer studies. The ability to form lipid nanoparticles (LNPs) further extends its application, providing a robust platform for delivering genetic material into target cells with precision and minimal toxicity.

Packaging

Avanti Research provides 16:0 DAP in a quantity of 25 mg and 200 mg powder packaging.

16:0 DAP embodies Avanti’s commitment to excellence and innovation. With a dedication to supporting cutting-edge research, Avanti Research stands as your trusted partner in your quest for scientific breakthroughs.


Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C37H73NO4
Percent Composition
C 74.57%, H 12.35%, N 2.35%, O 10.74%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
96326-74-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
595.98
Exact Mass
595.554
Synonyms
1,2-dihexadecanoyl-3-dimethylammonium-propane
Downloads
References

Amit M, Takahashi H, Dragomir MP, Lindemann A, Gleber-Netto FO, Pickering CR, Anfossi S, Osman AA, Cai Y, Wang R, Knutsen E, Shimizu M, Ivan C, Rao X, Wang J, Silverman DA, Tam S, Zhao M, Caulin C, Zinger A, Tasciotti E, Dougherty PM, El-Naggar A, Calin GA, Myers JN. Loss of p53 drives neuron reprogramming in head and neck cancer. Nature. 2020 Feb;578(7795):449-454. doi: 10.1038/s41586-020-1996-3. Epub 2020 Feb 12. PMID: 32051587.

 PubMed ID: 32051587
Certificates of Analysis

Related Products

860776
16:0 SB (DPSB) 16:0 SB (DPSB) Buy Now
860775
16:0 CB (DPCB) 16:0 CB (DPCB) Buy Now
700372
DC-cholesterol-d7 DC-cholesterol-d7 Buy Now
890900
ALC-0315 ALC-0315 Buy Now

Cart

Item Price Qty.
${ item.sku }
Base Price: $${ (item.price - (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150))).toFixed(2) }
Custom Packaging: +${ (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150)).toFixed(2) }
Change Custom Packaging 		$ ${ item.total.toFixed(2) }
Subtotal: ${ cart.itemSubtotal|money }
${ adjustment.name } ${ adjustment.amountAsCurrency }
Order Total: ${ cart.totalPriceAsCurrency }
Finalize Cart