890812 | VSA 1
Semisynthetic Saponin Adjuvant-VSA 1
Please Confirm Your Location
Effective March 1, 2018, Merck KGaA, Darmstadt, Germany* is the exclusive Distributor of Avanti Research. Research Products for all countries except the United States. For product pricing and order placement, please click on the appropriate Location Box below.
For customers located outside the United States, you will be redirected to www.sigmaaldrich.com/avanti prior to completing your purchase. Thank you for your continued business and support of Avanti Research!
*The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the U.S. and Canada
VSA 1
Semisynthetic Saponin Adjuvant-VSA 1
*Use only for intended field-of-use in human and animal vaccination research.*
VSA-1 is a semisynthetic saponin adjuvant prepared from naturally occurring and readily available Momordica saponin and capable of stimulating antigen-specific humoral and cellular immune responses. Its immunostimulating activity in enhancing the immune responses induced by the clinical glycoconjugate pneumococcal vaccine PCV13 is compared with QS-21 in female BALB/c mice. Both VSA-1 and QS-21 boosted IgG and opsonic antibodies titers against seven selected serotypes, including serotypes 3, 14, and 19A that are involved in most PCV13 breakthroughs.
C88H145NO39
C 57.41%, H 7.94%, N 0.76%, O 33.89%
CAS Registry Number is a Registered Trademark of the American Chemical Society
Powered by BiozJ. Med. Chem. 2019, 62, 21, 9976–9982 Publication Date:October 28, 2019 https://doi.org/10.1021/acs.jmedchem.9b01511
J. Med. Chem. 2022, 65, 21, 14589–14598 Publication Date:November 1, 2022 https://doi.org/10.1021/acs.jmedchem.2c01087
J. Med. Chem. 2020, 63, 6, 3290–3297 Publication Date:February 26, 2020 https://doi.org/10.1021/acs.jmedchem.9b02063
Vaccines (Basel) 2022 Aug 24;10(9):1383. https://doi.org/10.3390/vaccines10091383
Front Immunol. 2022 Dec 12:13:1079047. https://doi.org/10.3389/fimmu.2022.1079047
- Certificate of Analysis (Lot No. 890812P-5MG-A-010 and 7276PHA010)
