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890717 | 14:1 EPC (Tf Salt)

1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (Tf salt)

14:1 EPC (Tf Salt)

Oil

Size SKU Packaging Price
10mg 890717O-10mg 890717O-10mg 1 x 10mg $170.70
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Info

14:1 EPC (Tf Salt)

1,2-dimyristoleoyl-sn-glycero-3-ethylphosphocholine (Tf salt)

O-alkyl phosphatidylcholines constitute the first chemically stable triesters of biological lipid structures and the first cationic derivatives of phospholipids consisting entirely of biological metabolites linked with ester bonds. The lipid has low toxicity and is biodegradable.

Data
Hygroscopic
No
Light Sensitive
Yes
Molecular Formula
C39H73F3NO11PS
Percent Composition
C 54.98%, H 8.64%, F 6.69%, N 1.64%, O 20.66%, P 3.64%, S 3.76%
Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
1246304-44-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
852.031
Exact Mass
851.459
Synonyms
1,2-di-(9Z-tetradecenoyl)-sn-glycero-3-ethylphosphocholine (Tf salt)
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References

Koynova, R., Tenchov, B., Wang, L., MacDonald, R.C. (2009) Hydrophobic moiety of cationic lipids strongly modulates their transfection activity. Mol Pharm. 6:951-8. [PubMed]

 PubMed ID: 19341312

Tenchov, B.G., Wang, L., Koynova, R., MacDonald, R.C. (2008) Modulation of a membrane lipid lamellar-nonlamellar phase transition by cationic lipids: a measure for transfection efficiency. Biochim Biophys Acta. 1778:2405-12. [PubMed]

 PubMed ID: 18722340

Koynova, R., Tarahovsky, Y.S., Wang, L., MacDonald, R.C. (2007) Lipoplex formulation of superior efficacy exhibits high surface activity and fusogenicity, and readily releases DNA. Biochim Biophys Acta. 1768:375-86. [PubMed]

 PubMed ID: 17156744

Koynova, R., Wang, L., MacDonald, R.C. (2007) Synergy in lipofection by cationic lipid mixtures: superior activity at the gel-liquid crystalline phase transition. J Phys Chem B. 111:7786-95. [PubMed]

 PubMed ID: 17571876

Wang, L., MacDonald, R.C. (2007) Synergistic effect between components of mixtures of cationic amphipaths in transfection of primary endothelial cells. Mol Pharm. 4:615-23. [PubMed]

 PubMed ID: 17408283
Certificates of Analysis

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