880271 | DSPE-PEG(3400) Maleimide
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-3400] (ammonium salt)
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Info
DSPE-PEG(3400) Maleimide
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-3400] (ammonium salt)
| 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-3400] (ammonium salt), or DSPE-PEG(3400) Maleimide, is a functionalized PEG lipid that enhances ligand-mediated targeted drug delivery by facilitating bioactive molecule conjugation. Linking a maleimide group to DSPE-PEG(3400) allows precise attachment of antibodies, peptides, proteins, and aptamers that contain thiol, making it an effective tool for ligand-mediated targeted LNP formulations.DSPE-PEG(2000) Maleimide is being evaluated to improve the ligand-mediated targeting of lipid nanoparticles for numerous indications including genetic disorders, cancer therapies, neurological disorders, and rare disease. With the ability to bind bioactive molecules, it increases nanoparticle-based drug delivery systems’ specificity and efficacy. This lipid maintains exceptional purity due to precise synthesis techniques, ensuring no detectable maleimide ring opening, as verified by HNMR analysis. Its structural integrity makes it a trustworthy choice for nanoparticle formulation. |
Data
No
No
| C203H399N4O89P |
>99%
1 year
-20°C
4351.34
4348.66
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