DSPE PEG(2000)-N-Cyanine 5.5 880154 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000]-N-(Cyanine 5.5)

DSPE PEG (2000)-N-Cyanine 5.5 is a lipid-PEG conjugate with a Cyanine 5.5 dye attached.

DPSE is 1,2-distearoyl-sn-glycero-3-phosphoethanolamine. PEG(2000) stands for polyethylene glycol with a molecular weight of 2000. N-Cyanine 5.5 refers to cyanine 5.5, the near-infrared fluorescent dye commonly used in biological and biomedical research for imaging purposes. It emits light in the near-infrared spectrum, which can penetrate tissues more deeply than visible light. This makes Cyanine 5.5 suitable for in vivo imaging applications, such as tracking nanoparticles, cells, or biomolecules within living organisms.

This compound combines the properties of DSPE for lipid-based delivery systems, PEG for improved stability and solubility, and Cyanine 5.5 for near-infrared fluorescence imaging. DSPE PEG (2000)-N-Cyanine 5.5 is a fluorescent probe characterized by its peak emission of 635 nm. It serves as a valuable tool for assessing cell viability in cancer cells and investigating the kinetics of ciprofloxacin. Additionally, it exhibits photodynamic activity when exposed to light within the 400-1000 nm wavelength range.

Furthermore, it can be used in creating folic acid and Cyanine 5-modified vesicles derived from red blood cells. This use primarily involves demonstrating the incorporation of folic acid into red blood cells' membranes. When DSPE-PEG(2000)-N-Cyanine 5.5 is combined with red blood cells, the initially non-fluorescent membrane transforms into a vibrant Cyanine 5.5 fluorescence, allowing for easy visualization through a fluorescence microscope.