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880135 | DSPE-PEG(2000) Carboxylic Acid

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt)

DSPE-PEG(2000) Carboxylic Acid

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Size SKU Packaging Price
10mg 880135P-10mg 880135P-10mg 1 x 10mg $165.70
25mg 880135P-25mg 880135P-25mg 1 x 25mg $241.50
50mg 880135P-50mg 880135P-50mg 1 x 50mg $342.00
100mg 880135P-100mg 880135P-100mg 1 x 100mg $599.00
500mg 880135P-500mg 880135P-500mg 1 x 500mg $2,310.00
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Info

DSPE-PEG(2000) Carboxylic Acid

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt)

The chemical name for DSPE PEG 2000 Carboxylic Acid is 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)-2000] (sodium salt) or DSPE-PEG-COOH. Based on the polydispersity of PEG, its molecular weight is 2780.38, and its exact mass is 2778.7.

This specialized lipid molecule has been used in various applications in the field of biotechnology, pharmaceuticals, and drug delivery. It is a derivative of phospholipids and is part of the broader family of liposomal formulations.

The DSPE's hydrophobic characteristics facilitate the encapsulation and gathering of other hydrophobic drugs. In the presence of an activator like EDC or HATU, the -COOH group can readily react with primary amines, resulting in the formation of a stable amide bond.

DSPE-PEG 2000 carboxylic acid has been utilized to attach ITGA2 antibodies to liposome surfaces, create atosiban-conjugated liposomes, and produce dual complementary liposomes.

Avanti Research provides this 99% pure functionalized PEG lipid in powder form in 10 mg, 25 mg, 50 mg, 100 mg, and 500 mg packaging.

Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C131H257NNaO55P (average MW due to polydispersity of PEG)
Percent Composition

C 56.59%, H 9.32%, N 0.50%, Na 0.83%, O 31.65%, P 1.11%

Purity
>98%
Stability
1 Year
Storage Temperature
-20C
CAS Number
1403744-37-5
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
2780.38
Exact Mass
2778.7
Synonyms
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[acetyl-(polyethylene glycol)-2000-O-acetic acid] (sodium salt)
770135
Solubility in Different Solvents
Insoluble in DMSO, soluble in ethanol and Chloroform:Methanol (85:15) at 5mg/mL
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References

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