880129 | DSPE-PEG(2000) Biotin
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)-2000] (ammonium salt)

DSPE-PEG(2000) Biotin
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[biotinyl(polyethylene glycol)-2000] (ammonium salt)
Representative Structure
The molecular weight and exact mass are averages based on the polydispersity of PEG.
C142H280N5O56PS (average MW due to polydispersity of PEG)
C 56.54%, H 9.36%, N 2.32%, O 29.70%, P 1.03%, S 1.06%
CAS Registry Number is a Registered Trademark of the American Chemical Society
Bourn MD, Batchelor DVB, Ingram N, McLaughlan JR, Coletta PL, Evans SD, Peyman SA. High-throughput microfluidics for evaluating microbubble enhanced delivery of cancer therapeutics in spheroid cultures. J Control Release. 2020 Jun 17;326:13-24. doi: 10.1016/j.jconrel.2020.06.011. Epub ahead of print. PMID: 32562855.
PubMed ID: 32562855Beekers I, Mastik F, Beurskens R, Tang PY, Vegter M, van der Steen AFW, de Jong N, Verweij MD, Kooiman K. High-Resolution Imaging of Intracellular Calcium Fluctuations Caused by Oscillating Microbubbles. Ultrasound Med Biol. 2020 May 10:S0301-5629(20)30145-9. doi: 10.1016/j.ultrasmedbio.2020.03.029. Epub ahead of print. PMID: 32402676.
PubMed ID: 32402676Bohr SS, Thorlaksen C, Kühnel RM, Günther Pomorski T, Hatzakis NS. Label free fluorescence quantification of hydrolytic enzyme activity on native substrates reveal how lipase function depends on membrane curvature. Langmuir. 2020 May 21. doi: 10.1021/acs.langmuir.0c00787. Epub ahead of print. PMID: 32437165.
PubMed ID: 32437165Langeveld SAG, Schwieger C, Beekers I, Blaffert J, van Rooij T, Blume A, Kooiman K. Ligand Distribution and Lipid Phase Behavior in Phospholipid-Coated Microbubbles and Monolayers. Langmuir. 2020 Mar 31;36(12):3221-3233. doi: 10.1021/acs.langmuir.9b03912. Epub 2020 Mar 18. PMID: 32109064.
PubMed ID: 32109064Beekers I, Vegter M, Lattwein KR, Mastik F, Beurskens R, van der Steen AFW, de Jong N, Verweij MD, Kooiman K. Opening of endothelial cell-cell contacts due to sonoporation. J Control Release. 2020 Apr 1;322:426-438. doi: 10.1016/j.jconrel.2020.03.038. Epub ahead of print. PMID: 32246975.
PubMed ID: 32246975Khan MS, Kim JS, Hwang J, Choi Y, Lee K, Kwon Y, Jang J, Yoon S, Yang CS, Choi J. Effective delivery of mycophenolic acid by oxygen nanobubbles for modulating immunosuppression. Theranostics. 2020 Mar 4;10(9):3892-3904. doi: 10.7150/thno.41850. PMID: 32226527; PMCID: PMC7086369.
PubMed ID: 32226527Yin L, Masuyer G, Zhang S, Zhang J, Miyashita SI, Burgin D, Lovelock L, Coker SF, Fu TM, Stenmark P, Dong M. Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy. PLoS Biol. 2020 Mar 17;18(3):e3000618. doi: 10.1371/journal.pbio.3000618. PMID: 32182233; PMCID: PMC7077807.
PubMed ID: 32182233Langeveld SAG, Schwieger C, Beekers I, Blaffert J, van Rooij T, Blume A, Kooiman K. Ligand Distribution and Lipid Phase Behavior in Phospholipid-Coated Microbubbles and Monolayers. Langmuir. 2020 Mar 18. doi: 10.1021/acs.langmuir.9b03912. Epub ahead of print. PMID: 32109064.
PubMed ID: 32109064Durham ND, Howard AR, Govindan R, Senjobe F, Fels JM, Diehl WE, Luban J, Chandran K, Munro JB. Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics. Viruses. 2020 Jan 15;12(1):E103. doi: 10.3390/v12010103. PMID: 31952255.
PubMed ID: 31952255Wu B, Shang H, Liang X, Sun Y, Jing H, Han X, Cheng W. Preparation of novel targeting nanobubbles conjugated with small interfering RNA for concurrent molecular imaging and gene therapy in vivo. FASEB J. 2019 Dec;33(12):14129-14136. doi: 10.1096/fj.201900716RR. Epub 2019 Oct 26.
PubMed ID: 31657628Beguin E, Gray MD, Logan KA, Nesbitt H, Sheng Y, Kamila S, Barnsley LC, Bau L, McHale AP, Callan JF, Stride E. Magnetic microbubble mediated chemo-sonodynamic therapy using a combined magnetic-acoustic device. J Control Release. 2019 Nov 13;317:23-33. doi: 10.1016/j.jconrel.2019.11.013. [Epub ahead of print]
PubMed ID: 31733295Chen L, Mou S, Li F, Zeng Y, Sun Y, Horch RE, Wei W, Wang Z, Sun J. Self-Assembled Human Adipose-Derived Stem Cell-Derived Extracellular Vesicle-Functionalized Biotin-Doped Polypyrrole Titanium with Long-Term Stability and Potential Osteoinductive Ability. ACS Appl Mater Interfaces. 2019 Dec 11;11(49):46183-46196. doi: 10.1021/acsami.9b17015. Epub 2019 Nov 26.
PubMed ID: 31718127Godino E, López JN, Foschepoth D, Cleij C, Doerr A, Castellà CF, Danelon C. De novo synthesized Min proteins drive oscillatory liposome deformation and regulate FtsA-FtsZ cytoskeletal patterns. Nat Commun. 2019 Oct 31;10(1):4969. doi: 10.1038/s41467-019-12932-w.
PubMed ID: 31672986Crosio MA, Via MA, Cámara CI, Mangiarotti A, Del Pópolo MG, Wilke N. Interaction of a Polyarginine Peptide with Membranes of Different Mechanical Properties. Biomolecules. 2019 Oct 18;9(10). pii: E625. doi: 10.3390/biom9100625.
PubMed ID: 31635304Khan MS, Hwang J, Lee K, Choi Y, Seo Y, Jeon H, Hong JW, Choi J. Anti-Tumor Drug-Loaded Oxygen Nanobubbles for the Degradation of HIF-1α and the Upregulation of Reactive Oxygen Species in Tumor Cells. Cancers (Basel). 2019 Sep 29;11(10). pii: E1464. doi: 10.3390/cancers11101464.
PubMed ID: 31569523Shang H, Wu B, Liang X, Sun Y, Han X, Zhang L, Wang Q, Cheng W. Evaluation of therapeutic effect of targeting nanobubbles conjugated with NET-1 siRNA by shear wave elastography: an in vivo study of hepatocellular carcinoma bearing mice model. Drug Deliv. 2019 Dec;26(1):944-951. doi: 10.1080/10717544.2019.1667450.
PubMed ID: 31544556Jarin Z, Tsai FC, Davtyan A, Pak AJ, Bassereau P, Voth GA. Unusual Organization of I-BAR Proteins on Tubular and Vesicular Membranes. Biophys J. 2019 Aug 6;117(3):553-562. doi: 10.1016/j.bpj.2019.06.025. Epub 2019 Jul 2.
PubMed ID: 31349990Park S, Jackman JA, Cho NJ. Quantitative accounting of dye leakage and photobleaching in single lipid vesicle measurements: Implications for biomacromolecular interaction analysis. Colloids Surf B Biointerfaces. 2019 Jun 30;182:110338. doi: 10.1016/j.colsurfb.2019.06.067. [Epub ahead of print]
PubMed ID: 31301580Kim S, Sikes HD. Liposome-Enhanced Polymerization-Based Signal Amplification for Highly Sensitive Naked-Eye Biodetection in Paper-Based Sensors. ACS Appl Mater Interfaces. 2019 Aug 7;11(31):28469-28477. doi: 10.1021/acsami.9b08125. Epub 2019 Jul 26.
PubMed ID: 31291078Ditlev JA, Vega AR, Köster DV, Su X, Tani T, Lakoduk AM, Vale RD, Mayor S, Jaqaman K, Rosen MK. A composition-dependent molecular clutch between T cell signaling condensates and actin. Elife. 2019 Jul 3;8. pii: e42695. doi: 10.7554/eLife.42695.
PubMed ID: 31268421Su J, Wang J, Luo J, Li H. Ultrasound-mediated destruction of vascular endothelial growth factor (VEGF) targeted and paclitaxel loaded microbubbles for inhibition of human breast cancer cell MCF-7 proliferation. Mol Cell Probes. 2019 Aug;46:101415. doi: 10.1016/j.mcp.2019.06.005. Epub 2019 Jun 20.
PubMed ID: 31228519Mark S. Ferris, Makayla K. Elms, Kevin J. Cash. Enzyme‐conjugated nanosensors with tunable detection limits for small biomolecule determination. AlChE Journal. 11 June 2019. doi: 10.1002/aic.16698
Choi ES, Song J, Kang YY, Mok H. Mannose-Modified Serum Exosomes for the Elevated Uptake to Murine Dendritic Cells and Lymphatic Accumulation. Macromol Biosci. 2019 Jul;19(7):e1900042. doi: 10.1002/mabi.201900042. Epub 2019 May 29.
PubMed ID: 31141293Danni Wang, Yingzhi Zhang, Xiayu Zhao, Zhangrun Xu. Plasmonic colorimetric biosensor for visual detection of telomerase activity based on horseradish peroxidase-encapsulated liposomes and etching of Au nanobipyramids. Sensors and Actuators B: Chemical. 2019 October 1;296:126646. doi: 10.1016/j.snb.2019.126646.
Logan K, Foglietta F, Nesbitt H, Sheng Y, McKaig T, Kamila S, Gao J, Nomikou N, Callan B, McHale AP, Callan JF. Targeted chemo-sonodynamic therapy treatment of breast tumours using ultrasound responsive microbubbles loaded with paclitaxel, doxorubicin and Rose Bengal. Eur J Pharm Biopharm. 2019 Jun;139:224-231. doi: 10.1016/j.ejpb.2019.04.003. Epub 2019 Apr 5.
PubMed ID: 30959180Rasmus Eliasen, Thomas L. Andresen, Jannik B. Larsen. PEG‐Lipid Post Insertion into Drug Delivery Liposomes Quantified at the Single Liposome Level. Advanced Materials Interfaces. 2019 April 03. doi: 10.1002/admi.201801807
Alsahafi N, Bakouche N, Kazemi M, Richard J, Ding S, Bhattacharyya S, Das D, Anand SP, Prévost J, Tolbert WD, Lu H, Medjahed H, Gendron-Lepage G, Ortega Delgado GG, Kirk S, Melillo B, Mothes W, Sodroski J, Smith AB 3rd, Kaufmann DE, Wu X, Pazgier M, Rouiller I, Finzi A, Munro JB. An Asymmetric Opening of HIV-1 Envelope Mediates Antibody-Dependent Cellular Cytotoxicity. Cell Host Microbe. 2019 Apr 10;25(4):578-587.e5. doi: 10.1016/j.chom.2019.03.002.
PubMed ID: 30974085Lu M, Ma X, Castillo-Menendez LR, Gorman J, Alsahafi N, Ermel U, Terry DS, Chambers M, Peng D, Zhang B, Zhou T, Reichard N, Wang K, Grover JR, Carman BP, Gardner MR, Nikić-Spiegel I, Sugawara A, Arthos J, Lemke EA, Smith AB 3rd, Farzan M, Abrams C, Munro JB, McDermott AB, Finzi A, Kwong PD, Blanchard SC, Sodroski JG, Mothes W. Associating HIV-1 envelope glycoprotein structures with states on the virus observed by smFRET. Nature. 2019 Apr;568(7752):415-419. doi: 10.1038/s41586-019-1101-y. Epub 2019 Apr 10.
PubMed ID: 30971821Di Dong, Lian Zhu, Jiao Hu, Dai-Wen Pang, Zhi-Ling Zhang. Simple and rapid extracellular vesicles quantification via membrane biotinylation strategy coupled with fluorescent nanospheres-based lateral flow assay. Talanta. 2019 August 1;200:408-414. doi: 10.1016/j.talanta.2019.03.069
Horsley H, Owen J, Browning R, Carugo D, Malone-Lee J, Stride E, Rohn JL. Ultrasound-activated microbubbles as a novel intracellular drug delivery system for urinary tract infection. J Control Release. 2019 Mar 20;301:166-175. doi: 10.1016/j.jconrel.2019.03.017. [Epub ahead of print]
PubMed ID: 30904501Camille Simon, Rémy Kusters, Valentina Caorsi, Antoine Allard, Majdouline Abou-Ghali, John Manzi, Aurélie Di Cicco, Daniel Lévy, Martin Lenz, Jean-François Joanny, Clément Campillo, Julie Plastino, Pierre Sens, and Cécile Sykes. Actin dynamics drive cell-like membrane deformation. Nature Physics. 2019 March 18. doi: 10.1038/s41567-019-0464-1
Jing Y, Xiu-Juan Z, Hong-Jiao C, Zhi-Kui C, Qing-Fu Q, En-Sheng X, Li-Wu L. Ultrasound-targeted microbubble destruction improved the antiangiogenic effect of Endostar in triple-negative breast carcinoma xenografts. J Cancer Res Clin Oncol. 2019 Feb 25. doi: 10.1007/s00432-019-02866-7. [Epub ahead of print]
PubMed ID: 30805775Ren W, Ballou DR, FitzGerald R, Irudayaraj J. Plasmonic enhancement in lateral flow sensors for improved sensing of E. coli O157:H7. Biosens Bioelectron. 2019 Feb 1;126:324-331. doi: 10.1016/j.bios.2018.10.066. Epub 2018 Nov 1.
PubMed ID: 30453132Lin TW, Chien Y, Lin YY, Wang ML, Yarmishyn AA, Yang YP, Hwang DK, Peng CH, Hsu CC, Chen SJ, Chien KH. Establishing Liposome-Immobilized Dexamethasone-Releasing PDMS Membrane for the Cultivation of Retinal Pigment Epithelial Cells and Suppression of Neovascularization. Int J Mol Sci. 2019 Jan 9;20(2). pii: E241. doi: 10.3390/ijms20020241.
PubMed ID: 30634448Khan MS, Hwang J, Lee K, Choi Y, Jang J, Kwon Y, Hong JW, Choi J. Surface Composition and Preparation Method for Oxygen Nanobubbles for Drug Delivery and Ultrasound Imaging Applications. Nanomaterials (Basel). 2019 Jan 2;9(1). pii: E48. doi: 10.3390/nano9010048.
PubMed ID: 30609703Beguin E, Bau L, Shrivastava S, Stride E. Comparing Strategies for Magnetic Functionalization of Microbubbles. ACS Appl Mater Interfaces. 2019 Jan 16;11(2):1829-1840. doi: 10.1021/acsami.8b18418. Epub 2019 Jan 7.
PubMed ID: 30574777Pinon L, Montel L, Mesdjian O, Bernard M, Michel A, Ménager C, Fattaccioli J. Kinetically Enhanced Fabrication of Homogeneous Biomimetic and Functional Emulsion Droplets. Langmuir. 2018 Dec 18;34(50):15319-15326. doi: 10.1021/acs.langmuir.8b02721. Epub 2018 Dec 3.
PubMed ID: 30507132Liu Z, Zhang J, Tian Y, Zhang L, Han X, Wang Q, Cheng W. Targeted delivery of reduced graphene oxide nanosheets using multifunctional ultrasound nanobubbles for visualization and enhanced photothermal therapy. Int J Nanomedicine. 2018 Nov 22;13:7859-7872. doi: 10.2147/IJN.S181268. eCollection 2018.
PubMed ID: 30538464Olden BR, Perez CR, Wilson AL, Cardle II, Lin YS, Kaehr B, Gustafson JA, Jensen MC, Pun SH. Cell-Templated Silica Microparticles with Supported Lipid Bilayers as Artificial Antigen-Presenting Cells for T Cell Activation. Adv Healthc Mater. 2019 Jan;8(2):e1801188. doi: 10.1002/adhm.201801188. Epub 2018 Dec 13.
PubMed ID: 30549244Zhitomirsky B, Yunaev A, Kreiserman R, Kaplan A, Stark M, Assaraf YG. Lysosomotropic drugs activate TFEB via lysosomal membrane fluidization and consequent inhibition of mTORC1 activity. Cell Death Dis. 2018 Dec 13;9(12):1191. doi: 10.1038/s41419-018-1227-0.
PubMed ID: 30546014Maan R, Loiseau E, Bausch AR. Adhesion of Active Cytoskeletal Vesicles. Biophys J. 2018 Dec 18;115(12):2395-2402. doi: 10.1016/j.bpj.2018.10.013. Epub 2018 Oct 23.
PubMed ID: 30455042Tutkus M, Akhtar P, Chmeliov J, G Ouml Rf Ouml L F, Trinkunas G, Lambrev PH, Valkunas L. Fluorescence Microscopy of Single Liposomes with Incorporated Pigment-Proteins. Langmuir. 2018 Nov 1. doi: 10.1021/acs.langmuir.8b02307. [Epub ahead of print]
PubMed ID: 30380887Walsh SM, Mathiasen S, Christensen SM, Fay JF, King C, Provasi D, Borrero E, Rasmussen SGF, Fung JJ, Filizola M, Hristova K, Kobilka B, Farrens DL, Stamou D. Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs. Biophys J. 2018 Jul 17;115(2):300-312. doi: 10.1016/j.bpj.2018.05.036.
PubMed ID: 30021106- Certificate of Analysis (Lot No. 880129C-100MG-A-033 and 6291PLA033)
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