870606 | POVPC
1-palmitoyl-2-(5'-oxo-valeroyl)-sn-glycero-3-phosphocholine
Please Confirm Your Location
Effective March 1, 2018, Merck KGaA, Darmstadt, Germany* is the exclusive Distributor of Avanti Research. Research Products for all countries except the United States. For product pricing and order placement, please click on the appropriate Location Box below.
For customers located outside the United States, you will be redirected to www.sigmaaldrich.com/avanti prior to completing your purchase. Thank you for your continued business and support of Avanti Research!
*The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the U.S. and Canada
POVPC
1-palmitoyl-2-(5'-oxo-valeroyl)-sn-glycero-3-phosphocholine
CAS Registry Number is a Registered Trademark of the American Chemical Society
Powered by BiozThiagarajan D, Fiskesund R, Frostegård A, Steen J, Rahman M, Vikström M, Lundström S, Frostegård J. Immunoglobulin G1 Antibodies Against Phosphorylcholine Are Associated With Protection in Systemic Lupus Erythematosus and Atherosclerosis: Potential Underlying Mechanisms. ACR Open Rheumatol. 2020 Jun;2(6):344-356. doi: 10.1002/acr2.11127. Epub 2020 May 11. PMID: 32392632; PMCID: PMC7301871.
PubMed ID: 32392632Dong Y, Arif AA, Guo J, Ha Z, Lee-Sayer SSM, Poon GFT, Dosanjh M, Roskelley CD, Huan T, Johnson P. CD44 Loss Disrupts Lung Lipid Surfactant Homeostasis and Exacerbates Oxidized Lipid-Induced Lung Inflammation. Front Immunol. 2020 Jan 30;11:29. doi: 10.3389/fimmu.2020.00029. PMID: 32082314; PMCID: PMC7002364.
PubMed ID: 32082314Di Gioia M, Spreafico R, Springstead JR, Mendelson MM, Joehanes R, Levy D, Zanoni I.Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation. Nat Immunol. 2020 Jan;21(1):42-53. doi: 10.1038/s41590-019-0539-2. Epub 2019 Nov 25.
PubMed ID: 31768073Ouchi Y, Unoura K, Nabika H. Role of Oxidized Lipids in Permeation of H2O2 Through a Lipid Membrane: Molecular Mechanism of an Inhibitor to Promoter Switch. Sci Rep. 2019 Aug 29;9(1):12497. doi: 10.1038/s41598-019-48954-z.
PubMed ID: 31467337Ye Y, Wu T, Zhang T, Han J, Habazi D, Saxena R, Mohan C. Elevated oxidized lipids, anti-lipid autoantibodies and oxidized lipid immune complexes in active SLE. Clin Immunol. 2019 May 7;205:43-48. doi: 10.1016/j.clim.2019.05.004. [Epub ahead of print]
PubMed ID: 31075396Karki P, Meliton A, Shah A, Tian Y, Ohmura T, Sarich N, Birukova AA, Birukov KG. Role of truncated oxidized phospholipids in acute endothelial barrier dysfunction caused by particulate matter. PLoS One. 2018 Nov 12;13(11):e0206251. doi: 10.1371/journal.pone.0206251. eCollection 2018.
PubMed ID: 30419037Beranova, L., Cwiklik, L., Jurkiewicz, P., Hof, M., Jungwirth, P. (2010) Oxidation changes physical properties of phospholipid bilayers: fluorescence spectroscopy and molecular simulations. Langmuir 26:6140-4.
Turner, W.W., K. Hartvigsen, A. Boullier, E.N. Montano, J.L. Witztum, and M.S. VanNieuwenhze. (2012). Design and synthesis of a stable oxidized phospholipid mimic with specific binding recognition for macrophage scavenger receptors. J Med Chem 55:8178-82.
PubMed ID: 22934615Moumtzi, A., M. Trenker, K. Flicker, E. Zenzmaier, R. Saf, and A. Hermetter. (2007). Import and fate of fluorescent analogs of oxidized phospholipids in vascular smooth muscle cells. J Lipid Res 48:565-82.
PubMed ID: 17135656Ke Y, Karki P, Kim J, Son S, Berdyshev E, Bochkov VN, Birukova AA, Birukov KG. Elevated truncated oxidized phospholipids as a factor exacerbating ALI in the aging lungs. FASEB J. 2018 Dec 6:fj201800981R. doi: 10.1096/fj.201800981R. [Epub ahead of print].
PubMed ID: 30521374- Certificate of Analysis (Lot No. 870606P-1MG-A-018 and 6211PGA018)
- Certificate of Analysis (Lot No. 870606P-1MG-B-018 and 6211PGB018)
- Certificate of Analysis (Lot No. 870606P-1MG-C-018 and 6211PGC018)
- Certificate of Analysis (Lot No. 870606P-1MG-A-019_6211PGA019 and 6211PGA019)
- Certificate of Analysis (Lot No. 870606P-1MG-B-019 and 6211PGB019)
- Certificate of Analysis (Lot No. 870606P-1MG-C-019 and 6211PGC019)
- Certificate of Analysis (Lot No. 870606P-1MG-D-019 and 6211PGD019)
