860843 | 18:0(2S-OH) Sulfo GalCer
3-O-sulfo-D-galactosyl-ß1-1'-N-[2"(S)-hydroxystearoyl]-D-erythro-sphingosine (ammonium salt), (synthetic)
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18:0(2S-OH) Sulfo GalCer
3-O-sulfo-D-galactosyl-ß1-1'-N-[2"(S)-hydroxystearoyl]-D-erythro-sphingosine (ammonium salt), (synthetic)
18:0(2S-OH) Sulfo GalCer, also known as 3-O-sulfo-D-galactosyl-ß1-1'-N-[2"(S)-hydroxystearoyl]-D-erythro-sphingosine (Ammonium Salt), is a synthetic sulfated glycosphingolipid with the molecular formula C42H84N2O12S. This compound features a sphingosine backbone linked to a hydroxystearoyl fatty acid (18:0(2S-OH)) and a sulfated galactosyl head group.
Application
Sulfated galactosylceramides are crucial components of myelin, the protective sheath surrounding nerve fibers in both central and peripheral nervous systems. They play a critical role in maintaining myelin's structure and function while participating in cellular processes like cell-cell communication, protein trafficking, neuronal cell differentiation, and signal transduction. Their significance is particularly noted in regulating nerve conduction and stabilizing myelin membranes.
The synthetic form of 18:0(2S-OH) Sulfo GalCer is extensively utilized in neurobiological research, especially in studies of demyelinating diseases, including multiple sclerosis. This compound is a valuable tool for understanding the molecular mechanisms of myelination and the impact of sulfation on lipid function within the nervous system. Researchers can investigate the role of sulfated galactosylceramides in myelination and neurodegeneration, study their effects on signal transduction pathways, and analyze the molecular mechanisms underlying myelin stability.
Packaging
Avanti Research™ offers 18:0(2S-OH) Sulfo GalCer in powder form in 1mg packaging.
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Powered by Bioz- Certificate of Analysis (Lot No. 860843P-1MG-A-010 and 6134PGA010)
- Certificate of Analysis (Lot No. 860843P-1MG-C-010 and 6134PGC010)
