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860812 | 12:0(2S-OH) Ceramide

N-(2'-(S)-hydroxylauroyl)-D-erythro-sphingosine

12:0(2S-OH) Ceramide

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5mg 860812P-5mg 860812P-5mg 1 x 5mg $342.70
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12:0(2S-OH) Ceramide

N-(2'-(S)-hydroxylauroyl)-D-erythro-sphingosine

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C30H59NO4
Percent Composition
C 72.38%, H 11.95%, N 2.81%, O 12.86%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
1246298-45-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
497.794
Exact Mass
497.444
Synonyms
110974
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References

Szulc, Z. M., A. Bai, J. Bielawski, N. Mayroo, D. E. Miller, H. Gracz, Y. A. Hannun, and A. Bielawska. "Synthesis, NMR Characterization and Divergent Biological Actions of 2'-Hydroxy-Ceramide/Dihydroceramide Stereoisomers in MCF7 Cells." Bioorg Med Chem 18, no. 21 (2010): 7565-79. [PubMed]

 PubMed ID: 20851613

Hama, H. (2010) Fatty acid 2-Hydroxylation in mammalian sphingolipid biology. Biochim Biophys Acta. 1801:405-14. [PubMed]

PubMed ID: 20026285

Alderson, N.L., Hama, H. (2009) Fatty acid 2-hydroxylase regulates cAMP-induced cell cycle exit in D6P2T schwannoma cells. J Lipid Res. 50:1203-8. [PubMed]

 PubMed ID: 19171550

Herrero, A.B., Astudillo, A.M., Balboa, M.A., Cuevas, C., Balsinde, J., Moreno, S. (2008) Levels of SCS7/FA2H-mediated fatty acid 2-hydroxylation determine the sensitivity of cells to antitumor PM02734. Cancer Res. 68:9779-87. [PubMed]

 PubMed ID: 19047157
Certificates of Analysis

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