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860802 | RBM1-151

N-((2S,3R,E)-3-hydroxy-7-((2-oxo-2H-chromen-7-yl)oxy)hept-5-en-2-yl)dodecanamide

RBM1-151

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1mg 860802P-1mg 860802P-1mg 1 x 1mg $134.30
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RBM1-151

N-((2S,3R,E)-3-hydroxy-7-((2-oxo-2H-chromen-7-yl)oxy)hept-5-en-2-yl)dodecanamide

RBM1-151 is a coumarinic 1-deoxydihydroceramide that can be hydrolyzed by acid ceramidase, allowing for fluorescence measurement upon cleavage and thus enabling the quantification of enzyme activity. Due to this fluorescent ability, RBM1-151 is utilized in research to monitor the activity of lipid amidases within live cells. By combining RBM1-151 with specific irreversible inhibitors of AC (such as SACLAC) and FAAH (like URB597), researchers can estimate the activities of AC, NAAA, and FAAH in a single experiment. This capability is particularly useful in studies involving cancer cell lines, such as acute myeloid leukemia (AML) and melanoma, where these enzymes play significant roles.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C28H41NO5
Percent Composition
C 71.31%, H 8.76%, N 2.97%, O 16.96%
Purity
>99%
Stability
1 year
Storage Temperature
-20 °C
CAS Number
3077081-47-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
471.64
Exact Mass
471.3
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