860802 | RBM1-151
N-((2S,3R,E)-3-hydroxy-7-((2-oxo-2H-chromen-7-yl)oxy)hept-5-en-2-yl)dodecanamide
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Info
RBM1-151
N-((2S,3R,E)-3-hydroxy-7-((2-oxo-2H-chromen-7-yl)oxy)hept-5-en-2-yl)dodecanamide
| RBM1-151 is a coumarinic 1-deoxydihydroceramide that can be hydrolyzed by acid ceramidase, allowing for fluorescence measurement upon cleavage and thus enabling the quantification of enzyme activity. Due to this fluorescent ability, RBM1-151 is utilized in research to monitor the activity of lipid amidases within live cells. By combining RBM1-151 with specific irreversible inhibitors of AC (such as SACLAC) and FAAH (like URB597), researchers can estimate the activities of AC, NAAA, and FAAH in a single experiment. This capability is particularly useful in studies involving cancer cell lines, such as acute myeloid leukemia (AML) and melanoma, where these enzymes play significant roles. |
Data
No
No
C28H41NO5
C 71.31%, H 8.76%, N 2.97%, O 16.96%
>99%
1 year
-20 °C
CAS Number
3077081-47-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
CAS Registry Number is a Registered Trademark of the American Chemical Society
471.64
471.3
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