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860646 | C18 Ceramide (d17:1/18:0)

N-stearoyl-D-erythro-sphingosine (C17 base)

C18 Ceramide (d17:1/18:0)

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5mg 860646P-5mg 860646P-5mg 1 x 5mg $725.90
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Info

C18 Ceramide (d17:1/18:0)

N-stearoyl-D-erythro-sphingosine (C17 base)

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C35H69NO3
Percent Composition
C 76.16%, H 12.60%, N 2.54%, O 8.70%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
123065-42-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
551.927
Exact Mass
551.528
Synonyms
N-(octadecanoyl)-sphing-4-enine (C17 base)
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References

Ishida K, Takahashi A, Bito K, Draelos Z, Imokawa G. Treatment with Synthetic Pseudoceramide Improves Atopic Skin, Switching the Ceramide Profile to a Healthy Skin Phenotype. J Invest Dermatol. 2020 Feb 1:S0022-202X(20)30127-5. doi: 10.1016/j.jid.2020.01.014. Epub ahead of print. PMID: 32014509.

 PubMed ID: 32014509

Zalewska A, Maciejczyk M, Szulimowska J, Imierska M, Błachnio-Zabielska A. High-Fat Diet Affects Ceramide Content, Disturbs Mitochondrial Redox Balance, and Induces Apoptosis in the Submandibular Glands of Mice. Biomolecules. 2019 Dec 15;9(12):E877. doi: 10.3390/biom9120877. PMID: 31847462.

 PubMed ID: 31847462

Garić D, De Sanctis JB, Shah J, Dumut DC, Radzioch D. Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain. Prog Lipid Res. 2019 Mar 12;74:130-144. doi: 10.1016/j.plipres.2019.03.001. [Epub ahead of print]

 PubMed ID: 30876862

Feillet-Coudray C, Fouret G, Vigor C, Bonafos B, Jover B, Blachnio-Zabielska A, Rieusset J, Casas F, Gaillet S, Landrier JF, Durand T, Coudray C. Long-Term Measures of Dyslipidemia, Inflammation, and Oxidative Stress in Rats Fed a High-Fat/High-Fructose Diet. Lipids. 2019 Jan;54(1):81-97. doi: 10.1002/lipd.12128. Epub 2019 Feb 14.

 PubMed ID: 30767221

Usuki S, Tamura N, Tamura T, Higashiyama S, Tanji K, Mitsutake S, Inoue A, Aoki J, Mukai K, Igarashi Y. Konjac ceramide (kCer) regulates keratinocyte migration by Sema3A-like repulsion mechanism. Biochem Biophys Rep. 2019 Jan 3;17:132-138. doi: 10.1016/j.bbrep.2018.11.004. eCollection 2019 Mar.

 PubMed ID: 30623117

Blachnio-Zabielska AU, Hady HR, Markowski AR, Kurianiuk A, Karwowska A, Górski J, Zabielski P. Inhibition of Ceramide De Novo Synthesis Affects Adipocytokine Secretion and Improves Systemic and Adipose Tissue Insulin Sensitivity. Int J Mol Sci. 2018 Dec 11;19(12). pii: E3995. doi: 10.3390/ijms19123995.

 PubMed ID: 30545025

Wang Y, Fouret G, Bonafos B, Blachnio-Zabielska A, Leroy T, Crouzier D, Barea B, Gaillet S, Moro C, Lecomte J, Coudray C, Feillet-Coudray C. Long-term follow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high fructose diet-fed rats. J Nutr Biochem. 2019 Feb;64:182-197. doi: 10.1016/j.jnutbio.2018.10.021. Epub 2018 Nov 14.

 PubMed ID: 30530258
Certificates of Analysis

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