860636 | Glucosyl(ß) Sphingosine-d5
D-glucosyl-ß-1,1'-D-erythro-sphingosine-d5
Glucosyl(ß) Sphingosine-d5
D-glucosyl-ß-1,1'-D-erythro-sphingosine-d5
Glucosyl(β) Sphingosine-d5, also known as D-glucosyl-ß-1,1'-D-erythro-sphingosine-d5, is a powerful tool for researchers as a synthetic lipid labeled with deuterium. This unique compound serves as an internal standard for liquid chromatography-tandem mass spectrometry (LC-MS/MS) to ensure accurate quantification of lysohexosylceramide in various samples. Its stable isotopic composition provides an account of reliability and precision in complex analytical methods.
Application
This versatile lipid is essential for quantification, diagnosis, and analysis. It is used as an internal standard for LC-MS/MS, aiding in the study of lipidomics and metabolic pathways. It also finds usefulness in biomarker studies. It acts as a potential biomarker for Gaucher disease (GD). This facilitates the identification and monitoring of the lysosomal storage disorder.
Additionally, it is capable of regulating Ca2+ release. It provides insights into neurological functions and disorders thanks to its ability to regulate calcium release in brain microsomes.
Glucosyl(β) Sphingosine-d5 can also activate ion channels such as the nicotinic acetylcholine receptor by binding to the ligand binding site, furthermore proving its value in the study of neurotransmission.
Glucosyl(β) Sphingosine-d5 is integral to studying protein interactions and receptor activation. It provides a unique perspective on how synthetic lipids influence cellular processes, from ion channel regulation to peptide inhibition. Its role in regulating calcium release further underscores its importance in neurological research.
Packaging
Glucosyl(ß) Sphingosine-d5 is available in powder form in 1 mg packaging.
With a purity of over 99 percent, Avanti Research product ensures high reliability for critical research, backed by our expertise in lipid synthesis and analysis.
CAS Registry Number is a Registered Trademark of the American Chemical Society
Powered by BiozPolo G, Burlina AP, Ranieri E, Colucci F, Rubert L, Pascarella A, Duro G, Tummolo A, Padoan A, Plebani M, Burlina AB. Plasma and dried blood spot lysosphingolipids for the diagnosis of different sphingolipidoses: a comparative study. Clin Chem Lab Med. 2019 May 15. pii: /j/cclm.ahead-of-print/cclm-2018-1301/cclm-2018-1301.xml. doi: 10.1515/cclm-2018-1301. [Epub ahead of print]
PubMed ID: 31091195- Certificate of Analysis (Lot No. 860636P-1MG-B-011 and 6062PGB011)
- Certificate of Analysis (Lot No. 860636P-1MG-A-011 and 6062PGA011)
- Certificate of Analysis (Lot No. 860636P-CONF-A-011 and 6062PWA011)
- Certificate of Analysis (Lot No. 860636P-1MG-C-011 and 6062PGC011)
- Certificate of Analysis (Lot No. 860636P-1MG-D-011 and 6062PGD011)
- Certificate of Analysis (Lot No. 860636P-1MG-E-011 and 6062PGE011)
- Certificate of Analysis (Lot No. 860636P-1MG-F-011 and 6062PGF011)
- Certificate of Analysis (Lot No. 860636P-1MG-G-011 and 6062PGG011)
- Certificate of Analysis (Lot No. 860636P-1MG-H-011 and 6062PGH011)
- Certificate of Analysis (Lot No. 860636P-1MG-I-011 and 6062PGI011)
- Certificate of Analysis (Lot No. 860636P-1MG-J-011 and 6062PGJ011)
- Certificate of Analysis (Lot No. 860636P-1MG-K-011 and 6062PGK011)
- Certificate of Analysis (Lot No. 860636P-1MG-L-011 and 6062PGL011)
