860636 | Glucosyl(ß) Sphingosine-d5

D-glucosyl-ß-1,1'-D-erythro-sphingosine-d5

Glucosyl(ß) Sphingosine-d5

Powder

Size SKU Packaging Price
1mg 860636P-1mg 860636P-1mg 1 x 1mg $896.42
Request Bulk Pricing

Info

Glucosyl(ß) Sphingosine-d5

D-glucosyl-ß-1,1'-D-erythro-sphingosine-d5

Glucosyl(β) Sphingosine-d5, also known as D-glucosyl-ß-1,1'-D-erythro-sphingosine-d5, is a powerful tool for researchers as a synthetic lipid labeled with deuterium. This unique compound serves as an internal standard for liquid chromatography-tandem mass spectrometry (LC-MS/MS) to ensure accurate quantification of lysohexosylceramide in various samples. Its stable isotopic composition provides an account of reliability and precision in complex analytical methods.

Application

This versatile lipid is essential for quantification, diagnosis, and analysis. It is used as an internal standard for LC-MS/MS, aiding in the study of lipidomics and metabolic pathways. It also finds usefulness in biomarker studies. It acts as a potential biomarker for Gaucher disease (GD). This facilitates the identification and monitoring of the lysosomal storage disorder.

Additionally, it is capable of regulating Ca2+ release. It provides insights into neurological functions and disorders thanks to its ability to regulate calcium release in brain microsomes.

Glucosyl(β) Sphingosine-d5 can also activate ion channels such as the nicotinic acetylcholine receptor by binding to the ligand binding site, furthermore proving its value in the study of neurotransmission.

Glucosyl(β) Sphingosine-d5 is integral to studying protein interactions and receptor activation. It provides a unique perspective on how synthetic lipids influence cellular processes, from ion channel regulation to peptide inhibition. Its role in regulating calcium release further underscores its importance in neurological research.

Packaging

Glucosyl(ß) Sphingosine-d5 is available in powder form in 1 mg packaging.

With a purity of over 99 percent, Avanti Research product ensures high reliability for critical research, backed by our expertise in lipid synthesis and analysis.


Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C24H42D5NO7
Percent Composition
C 61.77%, H 11.23%, N 3.00%, O 24.00%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
1347831-14-4
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
466.663
Exact Mass
466.367
References

Polo G, Burlina AP, Ranieri E, Colucci F, Rubert L, Pascarella A, Duro G, Tummolo A, Padoan A, Plebani M, Burlina AB. Plasma and dried blood spot lysosphingolipids for the diagnosis of different sphingolipidoses: a comparative study. Clin Chem Lab Med. 2019 May 15. pii: /j/cclm.ahead-of-print/cclm-2018-1301/cclm-2018-1301.xml. doi: 10.1515/cclm-2018-1301. [Epub ahead of print]

PubMed ID: 31091195
Certificates of Analysis

Related Products

860695
Glucosyl(β) Sphingosine-d7 Glucosyl(β) Sphingosine-d7 Buy Now
330729
C15 Glucosyl(β) Ceramide-d7 (d18:1-d7/15:0) C15 Glucosyl(β) Ceramide-d7 (d18:1-d7/15:0) Buy Now
860673
C18:1 Glucosyl Ceramide-d5 C18:1 Glucosyl Ceramide-d5 Buy Now
860638
C18 Glucosyl(ß) Ceramide-d5 C18 Glucosyl(ß) Ceramide-d5 Buy Now

Cart

Item Price Qty.
${ item.sku }
Base Price: $${ (item.price - (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150))).toFixed(2) }
Custom Packaging: +${ (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150)).toFixed(2) }

Change Custom Packaging
$ ${ item.total.toFixed(2) }
Subtotal: ${ cart.itemSubtotal|money }
${ adjustment.name } ${ adjustment.amountAsCurrency }
Order Total: ${ cart.totalPriceAsCurrency }