860578 | C24 Mono-Sulfo Galactosyl(ß) Ceramide (d18:1/24:0)
3-O-sulfo-D-galactosyl-ß1-1'-N-lignoceroyl-D-erythro-sphingosine (ammonium salt), (synthetic)
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C24 Mono-Sulfo Galactosyl(ß) Ceramide (d18:1/24:0)
3-O-sulfo-D-galactosyl-ß1-1'-N-lignoceroyl-D-erythro-sphingosine (ammonium salt), (synthetic)
C24 mono-sulfo galactosyl(ß) ceramide (d18:1/24:0), also known as 3-O-sulfo-D-galactosyl-ß1-1'-N-lignoceroyl-D-erythro-sphingosine (Ammonium Salt), is a synthetic sulfated glycosphingolipid. With a molecular formula of C48H96N2O11S, it consists of a sphingosine backbone (d18:1), a lignoceroyl fatty acid (24:0), and a sulfated galactosyl head group.
Application
Sulfated galactosylceramides play a critical role in cellular processes in the nervous system. They are abundant in myelin, the insulating sheath around nerve fibers, contributing to membrane stability and function. These molecules are involved in cell-cell interactions, signal transduction, and the regulation of cell growth and differentiation.
C24 mono-sulfo galactosyl(ß) ceramide is essential for neurobiology research, helping with investigations into myelination, nerve function, and neurodegeneration. It aids in studying sulfated glycosphingolipids' impact on signal transduction pathways and their role in demyelinating diseases. Its specific functions make it vital for the nervous system, as it is implicated in neurodegenerative diseases and demyelinating disorders.
The synthetic version of C24 mono-sulfo galactosyl(ß) ceramide is a valuable tool for understanding the molecular mechanisms of myelination and demyelination and developing therapeutic strategies for conditions such as multiple sclerosis.
Packaging
Avanti Research™ provides C24 mono-sulfo galactosyl(ß) ceramide (d18:1/24:0) in powder form, available in 1 mg packaging.
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CAS Registry Number is a Registered Trademark of the American Chemical Society
3-O-sulfo-ß-D-C24-galactosylceramide (ammonium salt)
Powered by BiozRuhl CR, Pasko BL, Khan HS, Kindt LM, Stamm CE, Franco LH, Hsia CC, Zhou M, Davis CR, Qin T, Gautron L, Burton MD, Mejia GL, Naik DK, Dussor G, Price TJ, Shiloh MU. Mycobacterium tuberculosis Sulfolipid-1 Activates Nociceptive Neurons and Induces Cough. Cell. 2020 Apr 16;181(2):293-305.e11. doi: 10.1016/j.cell.2020.02.026. Epub 2020 Mar 5. PMID: 32142653; PMCID: PMC7102531.
PubMed ID: 32142653- Certificate of Analysis (Lot No. 860578P-1MG-A-011 and 6022PGA011)
- Certificate of Analysis (Lot No. 860578P-1MG-B-011 and 6022PGB011)
- Certificate of Analysis (Lot No. 860578P-1MG-C-011 and 6022PGC011)
- Certificate of Analysis (Lot No. 860578P-1MG-D-011 and 6022PGD011)
- Certificate of Analysis (Lot No. 860578P-1MG-E-011 and 6022PGE011)
- Certificate of Analysis (Lot No. 860578P-1MG-F-011 and 6022PGF011)
- Certificate of Analysis (Lot No. 860578P-1MG-G-011 and 6022PGG011)
