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860542 | Lactosyl(ß) Sphingosine (d18:1)

D-lactosyl-ß1-1'-D-erythro-sphingosine

Lactosyl(ß) Sphingosine (d18:1)

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5mg 860542P-5mg 860542P-5mg 1 x 5mg $348.25
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Lactosyl(ß) Sphingosine (d18:1)

D-lactosyl-ß1-1'-D-erythro-sphingosine

Lactosyl(ß) Sphingosine (d18:1), also known as Lactosylceramide or D-lactosyl-ß1-1'-D-erythro-sphingosine, is a glycosphingolipid composed of a sphingosine base (d18:1) linked to a lactosyl group, which is a disaccharide made up of glucose and galactose. With a molecular formula of C30H57NO12, this compound is a crucial intermediate in glycosphingolipid metabolism, serving as a precursor to more complex glycosphingolipids, such as gangliosides.

Lactosyl sphingosine is a glycosylsphingosine (Lyso-GSL) present in extracts of bovine brain white matter.

Application

Lactosyl(ß) Sphingosine plays a vital role in maintaining cell membrane structure, contributing to the stability and function of lipid bilayers. It is involved in various cellular processes, including cell adhesion, signaling, and differentiation. This molecule is essential in both normal physiological functions and the pathogenesis of certain diseases, including neurodegenerative disorders and cancer.

In research, Lactosylceramide is particularly valuable for studying the role of glycosphingolipids in cellular mechanisms. These include the regulation of apoptosis, immune responses, and the maintenance of cellular homeostasis. Given its central role in the glycosphingolipid biosynthetic pathway, Lactosyl(ß) Sphingosine is frequently utilized in studies exploring metabolic pathways and potential therapeutic targets for various diseases.

Packaging

Avanti Research™ provides D-lactosyl-ß1-1'-D-erythro-sphingosine in powder form in 5 mg packaging. Find more product information below.

Empower your research to push the boundaries of scientific discovery. Choose Avanti Research as your partner in lipid-based drug delivery, where cutting-edge innovation meets unwavering precision.


Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C30H57NO12
Percent Composition
C 57.76%, H 9.21%, N 2.25%, O 30.78%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
109785-20-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
623.773
Exact Mass
623.388
Synonyms
D-lactosyl-ß1-1' sphingosine
2S, 3R1-ß-lactosyl-sphing-4-enine
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References

Bodennec J, Pelled D, Futerman AH. Aminopropyl solid phase extraction and 2 D TLC of neutral glycosphingolipids and neutral lysoglycosphingolipids. J Lipid Res. 2003 Jan;44(1):218-26. doi: 10.1194/jlr.d200026-jlr200. PMID: 12518041.

 PubMed ID: 12518041
Certificates of Analysis

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