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860532 | C8 Ceramide-1-Phosphate (d18:1/8:0)

N-octanoyl-ceramide-1-phosphate (ammonium salt)

C8 Ceramide-1-Phosphate (d18:1/8:0)

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Info

C8 Ceramide-1-Phosphate (d18:1/8:0)

N-octanoyl-ceramide-1-phosphate (ammonium salt)

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C26H55N2O6P
Percent Composition
C 59.74%, H 10.61%, N 5.36%, O 18.37%, P 5.93%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
474943-70-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
522.698
Exact Mass
522.38
Synonyms
N-(octanoyl)-sphing-4-enine-1-phosphate
CerP(d18:1/8:0)
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References

Mena HA, Zubiry PR, Dizier B, Mignon V, Parborell F, Schattner M, Boisson-Vidal C, Negrotto S. Ceramide 1-Phosphate Protects Endothelial Colony-Forming Cells From Apoptosis and Increases Vasculogenesis In Vitro and In Vivo. Arterioscler Thromb Vasc Biol. 2019 Oct;39(10):e219-e232. doi: 10.1161/ATVBAHA.119.312766. Epub 2019 Aug 22.

 PubMed ID: 31434496

Gómez-Muñoz A, Kong JY, Salh B, Steinbrecher UP. Ceramide-1-phosphate blocks apoptosis through inhibition of acid sphingomyelinase in macrophages. J Lipid Res. 2004 Jan;45(1):99-105. Epub 2003 Oct 1.

 PubMed ID: 14523050

Hinkovska-Galcheva VT, Boxer LA, Mansfield PJ, Harsh D, Blackwood A, Shayman JA. The formation of ceramide-1-phosphate during neutrophil phagocytosis and its role in liposome fusion. J Biol Chem. 1998 Dec 11;273(50):33203-9.

 PubMed ID: 9837889

Gomez-Muñoz A, Duffy PA, Martin A, O'Brien L, Byun HS, Bittman R, Brindley DN. Short-chain ceramide-1-phosphates are novel stimulators of DNA synthesis and cell division: antagonism by cell-permeable ceramides. Mol Pharmacol. 1995 May;47(5):833-9.

 PubMed ID: 7746276
Certificates of Analysis

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