860524 | C24 Ceramide (d18:1/24:0)

N-lignoceroyl-D-erythro-sphingosine

C24 Ceramide (d18:1/24:0)

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Size SKU Packaging Price
5mg 860524P-5mg 860524P-5mg 1 x 5mg $213.40
10mg 860524P-10mg 860524P-10mg 1 x 10mg $382.00
50mg 860524P-50mg 860524P-50mg 1 x 50mg $1,510.50
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Info

C24 Ceramide (d18:1/24:0)

N-lignoceroyl-D-erythro-sphingosine

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C42H83NO3
Percent Composition
C 77.59%, H 12.87%, N 2.15%, O 7.38%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
102917-80-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
650.113
Exact Mass
649.637
Synonyms
N-(tetracosanoyl)-sphingosineN-(tetracosanoyl)-sphing-4-enine
CER(NS)
CER2(C24)
References

Aslan M, Afşar E, Kırımlıoglu E, Çeker T, Yılmaz Ç. Antiproliferative Effects of Thymoquinone in MCF-7 Breast and HepG2 Liver Cancer Cells: Possible Role of Ceramide and ER Stress. Nutr Cancer. 2020 Apr 14:1-13. doi: 10.1080/01635581.2020.1751216. Epub ahead of print. PMID: 32286088.

PubMed ID: 32286088

Afşar E, Kırımlıoglu E, Çeker T, Yılmaz Ç, Demir N, Aslan M. Effect of ER stress on sphingolipid levels and apoptotic pathways in retinal pigment epithelial cells. Redox Biol. 2020 Feb;30:101430. doi: 10.1016/j.redox.2020.101430. Epub 2020 Jan 20. PMID: 31978676; PMCID: PMC6976939.

PubMed ID: 31978676

Opalka L, Kovacik A, Pullmannová P, Maixner J, Vavrova K. Effects of omega-O-acylceramide structures and concentrations in healthy and diseased skin barrier lipid membrane models. J Lipid Res. 2019 Dec 19;jlr.RA119000420. doi: 10.1194/jlr.RA119000420. [Epub ahead of print]. PMID: 31857390.

PubMed ID: 31857390

Arshad H, Alfonso JCL, Franke R, Michaelis K, Araujo L, Habib A, Zboromyrska Y, Lücke E, Strungaru E, Akmatov MK, Hatzikirou H, Meyer-Hermann M, Petersmann A, Nauck M, Brönstrup M, Bilitewski U, Abel L, Sievers J, Vila J, Illig T, Schreiber J, Pessler F. Decreased plasma phospholipid concentrations and increased acid sphingomyelinase activity are accurate biomarkers for community-acquired pneumonia. J Transl Med. 2019 Nov 11;17(1):365. doi: 10.1186/s12967-019-2112-z.

PubMed ID: 31711507

Garić D, De Sanctis JB, Shah J, Dumut DC, Radzioch D. Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain. Prog Lipid Res. 2019 Mar 12;74:130-144. doi: 10.1016/j.plipres.2019.03.001. [Epub ahead of print]

PubMed ID: 30876862

Garić D, De Sanctis JB, Shah J, Dumut DC, Radzioch D. Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain. Prog Lipid Res. 2019 Mar 12;74:130-144. doi: 10.1016/j.plipres.2019.03.001. [Epub ahead of print]

PubMed ID: 30876862

Sochorová M, Audrlická P, Červená M, Kováčik A, Kopečná M, Opálka L, Pullmannová P, Vávrová K. Permeability and microstructure of cholesterol-depleted skin lipid membranes and human stratum corneum. J Colloid Interface Sci. 2019 Feb 1;535:227-238. doi: 10.1016/j.jcis.2018.09.104. Epub 2018 Oct 1.

PubMed ID: 30300812

Villanueva ME, Lanterna AE, Vico RV. Hydrophobic silver nanoparticles interacting with phospholipids and stratum corneum mimic membranes in Langmuir monolayers. J Colloid Interface Sci. 2019 May 1;543:247-255. doi: 10.1016/j.jcis.2019.02.069. Epub 2019 Feb 22.

PubMed ID: 30822659

Yao H, Gong J, Peterson AL, Lu X, Zhang P, Dennery PA. Fatty Acid Oxidation Protects Against Hyperoxia-Induced Endothelial Cell Apoptosis and Lung Injury in Neonatal Mice. Am J Respir Cell Mol Biol. 2018 Dec 20. doi: 10.1165/rcmb.2018-0335OC. [Epub ahead of print]

PubMed ID: 30571144

Özer H, Aslan İ, Oruç MT, Çöpelci Y, Afşar E, Kaya S, Aslan M. Early postoperative changes of sphingomyelins and ceramides after laparoscopic sleeve gastrectomy. Lipids Health Dis. 2018 Nov 24;17(1):269. doi: 10.1186/s12944-018-0917-z

PubMed ID: 30474555

Kováčik A, Šilarová M, Pullmannová P, Maixner J, Vávrová K. Effects of 6-Hydroxyceramides on the Thermotropic Phase Behavior and Permeability of Model Skin Lipid Membranes. Langmuir. 2017 Mar 21;33(11):2890-2899. doi: 10.1021/acs.langmuir.7b00184. Epub 2017 Mar 6.

PubMed ID: 28230380

Effects of 6-Hydroxyceramides on the Thermotropic Phase Behavior and Permeability of Model Skin Lipid Membranes Andrej Kováčik†, Michaela Šilarová†, Petra Pullmannová†, Jaroslav Maixner‡, and Kateřina Vávrová*† Langmuir, Article ASAP

PubMed ID: 28230380

Kováčik A, Pullmannová P, Maixner J, Vávrová K Effects of Ceramide and Dihydroceramide Stereochemistry at C-3 on the Phase Behavior and Permeability of Skin Lipid Membranes. Langmuir. 2017 Dec 26. doi: 10.1021/acs.langmuir.7b03448.

PubMed ID: 29228775

Kováčik A, Šilarová M, Pullmannová P, Maixner J, Vávrová K. Effects of 6-Hydroxyceramides on the Thermotropic Phase Behavior and Permeability of Model Skin Lipid Membranes. Langmuir. 2017 Mar 21;33(11):2890-2899. doi: 10.1021/acs.langmuir.7b00184. Epub 2017 Mar 6.

PubMed ID: 28230380
Certificates of Analysis

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