860469 | 3-deoxy sphingosine
(R,E)-2-aminooctadec-4-en-1-ol

Please Confirm Your Location
Effective March 1, 2018, Merck KGaA, Darmstadt, Germany* is the exclusive Distributor of Avanti Research. Research Products for all countries except the United States. For product pricing and order placement, please click on the appropriate Location Box below.
For customers located outside the United States, you will be redirected to www.sigmaaldrich.com/avanti prior to completing your purchase. Thank you for your continued business and support of Avanti Research!
*The life science business of Merck KGaA, Darmstadt, Germany operates as MilliporeSigma in the U.S. and Canada
3-deoxy sphingosine
(R,E)-2-aminooctadec-4-en-1-ol
3-deoxysphingosine is a structural analogue of the long chain sphingoid base, sphingosine. To our knowledge, the biological activity of this compound has not been thoroughly investigated.
CAS Registry Number is a Registered Trademark of the American Chemical Society
Santos TCB, Vaz A, Ventura AE, M Saied E, Arenz C, Fedorov A, Prieto M, Silva LC. Canonical and 1-Deoxy(methyl) Sphingoid Bases: Tackling the Effect of the Lipid Structure on Membrane Biophysical Properties. Langmuir. 2020 May 15. doi: 10.1021/acs.langmuir.0c01000. Epub ahead of print. PMID: 32369370.
PubMed ID: 32369370Mouts A, Vattulainen E, Matsufuji T, Kinoshita M, Matsumori N, Slotte JP. On the importance of the C(1)-OH and C(3)-OH functional groups of the long-chain base of ceramide for interlipid interaction and lateral segregation into ceramide-rich domains. Langmuir. 2018 Dec 3. doi: 10.1021/acs.langmuir.8b03237. [Epub ahead of print].
PubMed ID: 30507134Mouts A, Vattulainen E, Matsufuji T, Kinoshita M, Matsumori N, Slotte JP. On the importance of the C(1)-OH and C(3)-OH functional groups of the long-chain base of ceramide for interlipid interaction and lateral segregation into ceramide-rich domains. Langmuir 2018, 34, 51, 15864-15870.
PubMed ID: 30507134- Certificate of Analysis (Lot No. 860469P-1MG-A-015 and 5937PGA015)
- Certificate of Analysis (Lot No. 860469P-1MG-B-015 and 5937PGB015)
- Certificate of Analysis (Lot No. 860469P-1MG-C-015 and 5937PGC015)