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860409 | 9-PAHSA-d9

9-[((13,13,14,14,15,15,16,16,16-d9)palmitoyl)hydroxy]-stearic acid

9-PAHSA-d9

Chloroform

Size SKU Packaging Price
500µg 860409C-500ug 860409C-500ug $355.00
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Info

9-PAHSA-d9

9-[((13,13,14,14,15,15,16,16,16-d9)palmitoyl)hydroxy]-stearic acid

PAHSA levels correlate highly with insulin sensitivity and are reduced in adipose tissue and serum of insulin-resistant humans. In adipocytes, PAHSAs signal through GPR120 to enhance insulin-stimulated glucose uptake. Thus, FAHFAs are endogenous lipids with the potential to treat type 2 diabetes.
Avanti has obtained a license from the patent holder to manufacture these products for research use.
Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C34H57D9O4
Percent Composition
C 74.53%, H 13.79%, O 11.68%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
1809222-43-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
547.941
Exact Mass
547.553
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References

Kolar MJ, Kamat SS, Parsons WH, Homan EA, Maher T, Peroni OD, Syed I, Fjeld K, Molven A, Kahn BB, Cravatt BF, Saghatelian A. Branched Fatty Acid Esters of Hydroxy Fatty Acids Are Preferred Substrates of the MODY8 Protein Carboxyl Ester Lipase. Biochemistry. 2016 Aug 23;55(33):4636-41. doi: 10.1021/acs.biochem.6b00565. Epub 2016 Aug 10. PMID: 27509211; PMCID: PMC5056623.

 PubMed ID: 27509211

Yore MM, Syed I, Moraes-Vieira PM, Zhang T, Herman MA, Homan EA, Patel RT, Lee J, Chen S, Peroni OD, Dhaneshwar AS, Hammarstedt A, Smith U, McGraw TE, Saghatelian A, Kahn BB. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell. 2014 Oct 9;159(2):318-32. doi: 10.1016/j.cell.2014.09.035. PMID: 25303528; PMCID: PMC4260972.

 PubMed ID: 25303528
Certificates of Analysis

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