860355 | 16:0 PC-d62

1,2-dipalmitoyl-d62-sn-glycero-3-phosphocholine

16:0 PC-d62

Powder

Size SKU Packaging Price
10mg 860355P-10mg 860355P-10mg 1 x 10mg $157.10
25mg 860355P-25mg 860355P-25mg 1 x 25mg $280.75
100mg 860355P-100mg 860355P-100mg 1 x 100mg $754.00
200mg 860355P-200mg 860355P-200mg 1 x 200mg $1,130.00
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Chloroform

Size SKU Packaging Price
10mg 860355C-10mg 860355C-10mg 1 x 10mg 10mg/mL 1mL $157.10 157.1
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Info

16:0 PC-d62

1,2-dipalmitoyl-d62-sn-glycero-3-phosphocholine

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C40H18NO8PD62
Percent Composition
C 60.32%, H 2.28%, D 15.68%, N 1.76%, O 16.07%, P 3.89%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
25582-63-2
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
796.421
Exact Mass
795.951
References

Gravel AE, Arnold AA, Fillion M, Auger M, Warschawski DE, Marcotte I. Magnetically-orientable Tween-based model membranes for NMR studies of proteins. Biochim Biophys Acta Biomembr. 2020 May 29;1862(10):183379. doi: 10.1016/j.bbamem.2020.183379. Epub ahead of print. PMID: 32473826.

PubMed ID: 32473826

Vandera KA, Picconi P, Valero M, González-Gaitano G, Woods A, Zain NMM, Bruce KD, Clifton LA, Skoda MWA, Rahman KM, Harvey RD, Dreiss CA. Antibiotic-in-Cyclodextrin-in-Liposomes: Formulation Development and Interactions with Model Bacterial Membranes. Mol Pharm. 2020 May 26. doi: 10.1021/acs.molpharmaceut.0c00096. Epub ahead of print. PMID: 32352791.

PubMed ID: 32352791

Martial B, Raîche-Marcoux G, Lefèvre T, Audet P, Voyer N, Auger M. Structure of a Parkinson's Disease-Involved α-Synuclein Peptide Is Modulated by Membrane Composition and Physical State. J Phys Chem B. 2020 Apr 30;124(17):3469-3481. doi: 10.1021/acs.jpcb.0c00945. Epub 2020 Apr 20. PMID: 32227952.

PubMed ID: 32227952

Langeveld SAG, Schwieger C, Beekers I, Blaffert J, van Rooij T, Blume A, Kooiman K. Ligand Distribution and Lipid Phase Behavior in Phospholipid-Coated Microbubbles and Monolayers. Langmuir. 2020 Mar 31;36(12):3221-3233. doi: 10.1021/acs.langmuir.9b03912. Epub 2020 Mar 18. PMID: 32109064.

PubMed ID: 32109064

Phan MD, Korotych OI, Brady NG, Davis MM, Satija SK, Ankner JF, Bruce BD. X-ray and Neutron Reflectivity Studies of Styrene-Maleic Acid Copolymer Interactions with Galactolipid-Containing Monolayers. Langmuir. 2020 Apr 1. doi: 10.1021/acs.langmuir.9b03817. Epub ahead of print. PMID: 32207953.

PubMed ID: 32207953

Langeveld SAG, Schwieger C, Beekers I, Blaffert J, van Rooij T, Blume A, Kooiman K. Ligand Distribution and Lipid Phase Behavior in Phospholipid-Coated Microbubbles and Monolayers. Langmuir. 2020 Mar 18. doi: 10.1021/acs.langmuir.9b03912. Epub ahead of print. PMID: 32109064.

PubMed ID: 32109064

DiPasquale M, Nguyen MHL, Rickeard BW, Cesca N, Tannous C, Castillo SR, Katsaras J, Kelley EG, Heberle FA, Marquardt D. The antioxidant vitamin E as a membrane raft modulator: Tocopherols do not abolish lipid domains. Biochim Biophys Acta Biomembr. 2020 Jan 15:183189. doi: 10.1016/j.bbamem.2020.183189. Epub ahead of print. PMID: 31954106.

PubMed ID: 31954106

Leung SSW, Brewer J, Bagatolli LA, Thewalt JL. Measuring molecular order for lipid membrane phase studies: Linear relationship between Laurdan generalized polarization and deuterium NMR order parameter. Biochim Biophys Acta Biomembr. 2019 Dec 1;1861(12):183053. doi: 10.1016/j.bbamem.2019.183053. Epub 2019 Aug 28.

PubMed ID: 31472104

Rondelli V, Cola ED, Koutsioubas A, Alongi J, Ferruti P, Ranucci E, Brocca P. Mucin Thin Layers: A Model for Mucus-Covered Tissues. Int J Mol Sci. 2019 Jul 29;20(15). pii: E3712. doi: 10.3390/ijms20153712.

PubMed ID: 31362433

Richard-Lacroix M, Umuhire KN, Lister E, Pellerin C, Badia A. Selective Isotopic Labeling Resolves the Gel-to-Fluid Phase Transitions of the Individual Leaflets of a Planar-Supported Phospholipid Bilayer. Langmuir. 2019 Jul 30;35(30):9912-9922. doi: 10.1021/acs.langmuir.9b00747. Epub 2019 Jul 17.

PubMed ID: 31277548

Goussous SA, Fellows AP, Casford MTL, Davies PB. A time domain study of surfactin penetrating a phospholipid monolayer at the air-water interface investigated using sum frequency generation spectroscopy, infrared reflection absorption spectroscopy, and AFM-nano infrared microscopy. Biochim Biophys Acta Biomembr. 2019 Jun 12;1861(9):1568-1578. doi: 10.1016/j.bbamem.2019.06.004. [Epub ahead of print]

PubMed ID: 31199896

Hughes AV, Patel DS, Widmalm G, Klauda JB, Clifton LA, Im W. Physical Properties of Bacterial Outer Membrane Models: Neutron Reflectometry & Molecular Simulation. Biophys J. 2019 Mar 19;116(6):1095-1104. doi: 10.1016/j.bpj.2019.02.001. Epub 2019 Feb 10.

PubMed ID: 30850116

Kawana H, Kano K, Shindou H, Inoue A, Shimizu T, Aoki J. An accurate and versatile method for determining the acyl group-introducing position of lysophospholipid acyltransferases. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Mar 7. pii: S1388-1981(18)30310-X. doi: 10.1016/j.bbalip.2019.02.008. [Epub ahead of print]

PubMed ID: 30853650

Hughes AV, Patel DS, Widmalm G, Klauda JB, Clifton LA, Im W. Physical Properties of Bacterial Outer Membrane Models: Neutron Reflectometry & Molecular Simulation. Biophys J. 2019 Mar 19;116(6):1095-1104. doi: 10.1016/j.bpj.2019.02.001. Epub 2019 Feb 10.

PubMed ID: 30850116

Terakosolphan W, Trick JL, Royall PG, Rogers SE, Lamberti O, Lorenz CD, Forbes B, Harvey RD. Glycerol solvates DPPC headgroups and localises in the interfacial regions of model pulmonary interfaces altering bilayer structure. Langmuir. 2018 May 8. doi: 10.1021/acs.langmuir.8b00866.


Kenneth P. Mineart, Shrinivas Venkataraman, Yi Yan Yang, James L. Hedrick and Vivek M. Prabhu. Fabrication and Characterization of Hybrid Stealth Liposomes. Macromolecules, Article ASAP


Marquardt, D., Herberle, F.A., Miti, T., Eicher, B., London, E., Katsaras, J., Pabst, G. (2017). 1H NMR Shows Slow Phospholipid Flip-Flop in Gel and Fluid Bilayers. Langmuir.

PubMed ID: 28106399

Disordering Effects of Digitonin on Phospholipid Monolayers M. Orczyk, K. Wojciechowski , and G. Brezesinski Langmuir, Article ASAP

PubMed ID: 28333465

Ausili A, Torrecillas A, deGodos AM, Corbalan-Garcia S, Gomez-Fernandez JC. The phenolic group of α-tocopherol anchors in the lipid-water interface of fully saturated membranes. Langmuir. 2018 Feb 15. doi: 10.1021/acs.langmuir.7b04142. [Epub ahead of print]

PubMed ID: 29447442
Certificates of Analysis

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