860345 | 14:0 PC-d54

1,2-dimyristoyl-d54-sn-glycero-3-phosphocholine

14:0 PC-d54

Chloroform

Size SKU Packaging Price
10mg 860345C-10mg 860345C-10mg 1 x 10mg 10mg/mL 1mL $157.10
Request Bulk Pricing

Powder

Size SKU Packaging Price
10mg 860345P-10mg 860345P-10mg 1 x 10mg $157.10 157.1
25mg 860345P-25mg 860345P-25mg 1 x 25mg $280.75 280.75
100mg 860345P-100mg 860345P-100mg 1 x 100mg $754.00 754
200mg 860345P-200mg 860345P-200mg 1 x 200mg $1,130.00 1130
Request Bulk Pricing

Info

14:0 PC-d54

1,2-dimyristoyl-d54-sn-glycero-3-phosphocholine

Deuterated fatty acids experience exchange of the deuteriums on the alpha carbon to the carbonyl, i.e., C2 position, and will therefore be a mixture of compounds that are fully deuterated and partially deuterated at that position.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C36H18NO8PD54
Percent Composition
C 59.05%, H 2.48%, D 14.85%, N 1.91%, O 17.48%, P 4.23%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
78415-49-3
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
732.265
Exact Mass
731.838
Synonyms
DMPC-D54
Solubility in Different Solvents
Insoluble in DMSO, soluble in ethanol and Chloroform:Methanol:Water (65:25:4) at 5mg/mL
References

Ghosh U, Weliky DP. 2H nuclear magnetic resonance spectroscopy supports larger amplitude fast motion and interference with lipid chain ordering for membrane that contains β sheet human immunodeficiency virus gp41 fusion peptide or helical hairpin influenza virus hemagglutinin fusion peptide at fusogenic pH. Biochim Biophys Acta Biomembr. 2020 Jun 23;1862(10):183404. doi: 10.1016/j.bbamem.2020.183404. Epub ahead of print. PMID: 32585207.

PubMed ID: 32585207

Gravel AE, Arnold AA, Fillion M, Auger M, Warschawski DE, Marcotte I. Magnetically-orientable Tween-based model membranes for NMR studies of proteins. Biochim Biophys Acta Biomembr. 2020 May 29;1862(10):183379. doi: 10.1016/j.bbamem.2020.183379. Epub ahead of print. PMID: 32473826.

PubMed ID: 32473826

Hall SCL, Clifton LA, Tognoloni C, Morrison KA, Knowles TJ, Kinane CJ, Dafforn TR, Edler KJ, Arnold T. Adsorption of a styrene maleic acid (SMA) copolymer-stabilized phospholipid nanodisc on a solid-supported planar lipid bilayer. J Colloid Interface Sci. 2020 Apr 11;574:272-284. doi: 10.1016/j.jcis.2020.04.013. Epub ahead of print. PMID: 32330753.

PubMed ID: 32330753

Drew DL Jr, Butcher B, Sahu ID, Ahammad T, Dixit G, Lorigan GA. Active S2168 and inactive S21IRS pinholin interact differently with the lipid bilayer: A 31P and 2H solid state NMR study. Biochim Biophys Acta Biomembr. 2020 Jul 1;1862(7):183257. doi: 10.1016/j.bbamem.2020.183257. Epub 2020 Mar 5. PMID: 32147355.

PubMed ID: 32147355

Ausili A, Clemente J, Pons-Belda ÓD, de Godos A, Corbalán-García S, Torrecillas A, Teruel JA, Ghmez-Fernández JC. Interaction of Vitamin K1 and Vitamin K2 with Dimyristoylphosphatidylcholine and Their Location in the Membrane. Langmuir. 2020 Feb 4;36(4):1062-1073. doi: 10.1021/acs.langmuir.9b03552. Epub 2020 Jan 23. PMID: 31927934.

PubMed ID: 31927934

Schmidt ML, Davis JH. 2 H NMR of oriented phospholipid/cholesterol bilayers containing an amphiphilic peptide. Biochim Biophys Acta Biomembr. 2020 Jan 18;1862(5):183196. doi: 10.1016/j.bbamem.2020.183196. Epub ahead of print. PMID: 31958437.

PubMed ID: 31958437

Li J, Zhang Y, Soubias O, Khago D, Chao FA, Li Y, Shaw K, Byrd RA. Optimization of sortase A ligation for flexible engineering of complex protein systems. J Biol Chem. 2020 Jan 23:jbc.RA119.012039. doi: 10.1074/jbc.RA119.012039. Epub ahead of print. PMID: 31974162.

PubMed ID: 31974162

Jiang T, Hall A, Eres M, Hemmatian Z, Qiao B, Zhou Y, Ruan Z, Couse AD, Heller WT, Huang H, de la Cruz MO, Rolandi M, Xu T. Single-chain heteropolymers transport protons selectively and rapidly. Nature. 2020 Jan;577(7789):216-220. doi: 10.1038/s41586-019-1881-0. Epub 2020 Jan 8. PMID: 31915399.

PubMed ID: 31915399

Nordström R, Browning KL, Parra-Ortiz E, Damgaard LSE, Häffner SM, Maestro A, Campbell RA, Cooper JFK, Malmsten M. Membrane interactions of antimicrobial peptide-loaded microgels. J Colloid Interface Sci. 2020 Mar 7;562:322-332. doi: 10.1016/j.jcis.2019.12.022. Epub 2019 Dec 9. PMID: 31855795.

PubMed ID: 31855795

Sharma VK, Nagao M, Rai DK, Mamontov E. Membrane softening by nonsteroidal anti-inflammatory drugs investigated by neutron spin echo. Phys Chem Chem Phys. 2019 Sep 18;21(36):20211-20218. doi: 10.1039/c9cp03767e.

PubMed ID: 31486459

Nguyen MHL, DiPasquale M, Rickeard BW, Doktorova M, Heberle FA, Scott HL, Barrera FN, Taylor G, Collier CP, Stanley CB, Katsaras J, Marquardt D. Peptide-Induced Lipid Flip-Flop in Asymmetric Liposomes Measured by Small Angle Neutron Scattering. Langmuir. 2019 Sep 10;35(36):11735-11744. doi: 10.1021/acs.langmuir.9b01625. Epub 2019 Aug 27.

PubMed ID: 31408345

Müller S, Schwieger C, Gruhle K, Garamus VM, Hause G, Meister A, Drescher S. Azide-Modified Membrane Lipids: Miscibility with Saturated Phosphatidylcholines. Langmuir. 2019 Sep 24;35(38):12439-12450. doi: 10.1021/acs.langmuir.9b01842. Epub 2019 Sep 10.

PubMed ID: 31456406

Nicolas I, Bordeau V, Bondon A, Baudy-Floc'h M, Felden B. Novel antibiotics effective against gram-positive and -negative multi-resistant bacteria with limited resistance. PLoS Biol. 2019 Jul 9;17(7):e3000337. doi: 10.1371/journal.pbio.3000337. eCollection 2019 Jul.

PubMed ID: 31287812

Fu Q, Piai A, Chen W, Xia K, Chou JJ. Structure determination protocol for transmembrane domain oligomers. Nat Protoc. 2019 Aug;14(8):2483-2520. doi: 10.1038/s41596-019-0188-9. Epub 2019 Jul 3.

PubMed ID: 31270510

Sergey A. Kotenkov, Oleg I. Gnezdilov, Aliya V. Khaliullina, Oleg N. Antzutkin, Roustam S. Gimatdinov, Andrei V. Filippov. Effect of Cholesterol and Curcumin on Ordering of DMPC Bilayers. Applied Magnetic Resonance. 2018 Nov 23. doi: 10.1007/s00723-018-1102-2


Divakara MB, Martinez D, Ravi A, Bhavana V, Ramana V, Habenstein B, Loquet A, Santosh MS. Molecular mechanisms for the destabilization of model membranes by islet amyloid polypeptide. Biophys Chem. 2019 Feb;245:34-40. doi: 10.1016/j.bpc.2018.12.002. Epub 2018 Dec 14.

PubMed ID: 30576976

Sauvage F, Legrand FX, Roux M, Rajkovic I, Weiss TM, Varga Z, Augis L, Nugue G, Debouzy JC, Vergnaud-Gauduchon J, Barratt G. Interaction of dequalinium chloride with phosphatidylcholine bilayers: A biophysical study with consequences on the development of lipid-based mitochondrial nanomedicines. J Colloid Interface Sci. 2019 Mar 1;537:704-715. doi: 10.1016/j.jcis.2018.11.059. Epub 2018 Nov 15.

PubMed ID: 30497059

Miranda C, Booth VK, Morrow MR. Effects of Amphipathic Polypeptides on Membrane Organization Inferred from Studies Using Bicellar Lipid Mixtures. Langmuir. 2018 Sep 20. doi: 10.1021/acs.langmuir.8b02257. [Epub ahead of print]

PubMed ID: 30196696

Harmouche N, Bechinger B. Lipid-Mediated Interactions between the Antimicrobial Peptides Magainin 2 and PGLa in Bilayers. Biophys J. 2018 Aug 16. pii: S0006-3495(18)30936-6. doi: 10.1016/j.bpj.2018.08.009. [Epub ahead of print]

PubMed ID: 30195937

Yang M, Wang K, Lin J, Wang L, Wei F, Zhu JT, Zheng W, Shen L. Gel Phase Membrane Retards Amyloid β-peptide (1-42) Fibrillation by Restricting Slaved Diffusion of Peptides on Lipid Bilayers. Langmuir. 2018 Jun 20. doi: 10.1021/acs.langmuir.8b01315. [Epub ahead of print

PubMed ID: 29925241

Roux, M., E. Sternin, V. Bonnet, C. Fajolles, and F. Djedaini-Pilard. (2013). Dynamic Lipid Lateral Segregation Driven by Lauryl Cyclodextrin Interactions at the Membrane Surface. Langmuir

PubMed ID: 23409976

Liquid Disordered–Liquid Ordered Phase Coexistence in Lipid/Cholesterol Mixtures: A Deuterium 2D NMR Exchange Study Miranda L. Schmidt and James H. Davis* University of Guelph, Department of Physics, 50 Stone Road East, Guelph, Ontario, Canada, N1G 2W1 Langmuir, Article ASAP DOI: 10.1021/acs.langmuir.6b02834 Publication Date (Web): February 6, 2017 Copyright © 2017 American Chemical Society

PubMed ID: 28165749

The Conformation of the Epidermal Growth Factor Receptor Transmembrane Domain Dimer Dynamically Adapts to the Local Membrane EnvironmentEduard V. Bocharov*† , Pavel E. Bragin†, Konstantin V. Pavlov†, Olga V. Bocharova†, Konstantin S. Mineev†, Anton A. Polyansky†‡ , Pavel E. Volynsky†, Roman G. Efremov†§, and Alexander S. Arseniev† Biochemistry, Article ASAP

PubMed ID: 28291355

Reconciling Differences between Lipid Transfer in Free-Standing and Solid Supported Membranes: A Time-Resolved Small-Angle Neutron Scattering Study Benny Wah†, Jeffrey M. Breidigan†, Joseph Adams†, Piotr Horbal†, Sumit Garg†∥, Lionel Porcar‡§, and Ursula Perez-Salas*†∥ Langmuir, Article ASAP

PubMed ID: 28300412

Ausili A, Torrecillas A, deGodos AM, Corbalan-Garcia S, Gomez-Fernandez JC. The phenolic group of α-tocopherol anchors in the lipid-water interface of fully saturated membranes. Langmuir. 2018 Feb 15. doi: 10.1021/acs.langmuir.7b04142. [Epub ahead of print]

PubMed ID: 29447442
Certificates of Analysis

Related Products

860805
PAzePC-d5 PAzePC-d5 Buy Now
860804
PGPC-d5 PGPC-d5 Buy Now
860300
16:0 Lyso PC-d5 16:0 Lyso PC-d5 Buy Now

Cart

Item Price Qty.
${ item.sku }
Base Price: $${ (item.price - (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150))).toFixed(2) }
Custom Packaging: +${ (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150)).toFixed(2) }

Change Custom Packaging
${ item.salePriceAsCurrency }
Subtotal: ${ cart.itemSubtotal|money }
${ adjustment.type }: ${ adjustment.name } ${ adjustment.amountAsCurrency }
${ adjustment.name } ${ adjustment.amountAsCurrency }
Order Total: ${ cart.totalPriceAsCurrency }

Have a promo code? Enter it in your cart to apply your discount and enjoy the savings on your purchase! Finalize Cart