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860122 | C18:0-d7 GM3 Ceramide (d18:1/18:0-d7), synthetic

C18:0-d7 GM3 Ganglioside (Neu5Aca2,3Galb1,4Glcb-Ceramide(d18:1/18:0-d7))

C18:0-d7 GM3 Ceramide (d18:1/18:0-d7), synthetic

Methanol

Size SKU Packaging Price
100µg 860122W-100µg 860122W-100µg $199.00
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Info

C18:0-d7 GM3 Ceramide (d18:1/18:0-d7), synthetic

C18:0-d7 GM3 Ganglioside (Neu5Aca2,3Galb1,4Glcb-Ceramide(d18:1/18:0-d7))

C18:0-d7 GM3 ceramide (d18:1/18:0-d7), also known as C18:0-d7 GM3 ganglioside, is a synthetic, deuterium-labeled analog of naturally occurring GM3. This compound, with a formula of C59H101D7N2O21, features a sphingosine backbone (d18:1), a stearoyl fatty acid chain with seven deuterium atoms (18:0-d7), and an oligosaccharide chain that includes a sialic acid (Neu5Ac) residue.

Application

GM3 gangliosides are fundamental members of the ganglioside family, serving as precursors for more complex gangliosides. They are present in cell membranes, especially in the nervous system, and play key roles in cell signaling, cell cycle arrest, cell differentiation, communication, and growth factor receptor modulation. In glioma cells, C18 ceramide contributes to cell death. These functions make GM3 highly relevant in cancer research, where it influences tumor progression, and cardiovascular studies, where it’s linked to insulin resistance and metabolic syndrome.

Moreover, GM3 regulates immune responses and impacts cellular signaling pathways in various metabolic conditions. Deuterium labeling (d7) enables precise tracking of GM3’s metabolic routes, making it invaluable for studying glycosphingolipid dynamics in health and disease. This makes C18:0-d7 GM3 ceramide ideal for research into cancer, cardiovascular diseases, and immune-related conditions, as well as fundamental studies in cell signaling.

Packaging

Avanti Research™ offers C18:0-d7 GM3 Ceramide (d18:1/18:0-d7) in methanol form, packaged as 100µg, so you can continue making world-changing discoveries and a significant difference in research and development.

Choose Avanti Research for expertise backed by 50+ years of experience and 250K+ customer publications. We’re not just setting lipid research standards—we’re advancing them to empower your most ambitious goals.


Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula

C59H101D7N2O21

Percent Composition
C 59.62%, H 9.75%, N 2.36%, O 28.27%
Purity
95%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
3056013-66-9
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
1188.55
Exact Mass
1187.79
Downloads
Certificates of Analysis

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