860121 | C18:0-d7 GM2 Ceramide (d18:1/18:0-d7), synthetic
C18:0-d7 GM2 Ganglioside (GalNAcb1,4(Neu5Aca2,3)Galb1,4Glcb-Ceramide(d18:1/18:0-d7))

C18:0-d7 GM2 Ceramide (d18:1/18:0-d7), synthetic
C18:0-d7 GM2 Ganglioside (GalNAcb1,4(Neu5Aca2,3)Galb1,4Glcb-Ceramide(d18:1/18:0-d7))
C18:0-d7 GM2 ceramide (d18:1/18:0-d7), also known as C18:0-d7 GM2 ganglioside or C18:0-d7 GM2 ganglioside (GalNAcb1,4(Neu5Aca2,3)Galb1,4Glcb-Ceramide(d18:1/18:0-d7)), is a synthetic, deuterium-labeled analog of the naturally occurring GM2 ganglioside. This compound features a sphingosine backbone (d18:1), a stearoyl fatty acid chain labeled with seven deuterium atoms (18:0-d7), and an oligosaccharide chain that includes a sialic acid (Neu5Ac) residue linked to an N-acetylgalactosamine (GalNAc) residue.
Application
GM2 gangliosides are primarily found in the nervous system and are critical to the structure and function of neuronal cell membranes. They play a key role in modulating cell signaling, particularly in the brain, where they influence neuronal growth, differentiation, and synaptic function. GM2 is also a key molecule involved in lysosomal storage diseases such as Tay-Sachs disease, making it a significant focus in neurodegenerative research.
The deuterium labeling (d7) in this synthetic version allows for precise tracking in metabolic studies and provides an essential tool for researchers investigating the role of GM2 in cellular processes and disease mechanisms, particularly in the context of neurodegenerative disorders.
Packaging
Avanti Research™ provides C18:0-d7 GM2 Ceramide (d18:1/18:0-d7) in methanol form in 100µg packaging to keep your research on the right path.
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C67H114D7N3O26
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- Certificate of Analysis (Lot No. 860121W-100UG-A-010 and 7194WDA010)