860089 | C18:0 GT1b (d18:1/18:0)
C18:0 trisialoganglioside-GT1b (d18:1/18:0, triammonium salt)
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C18:0 GT1b (d18:1/18:0)
C18:0 trisialoganglioside-GT1b (d18:1/18:0, triammonium salt)
C18:0 GT1b is a trisialoganglioside. It belongs to the group of gangliosides, composed of glycosphingolipids and three sialic acids.
Gangliosides occur predominantly on the outer surface of cell membranes and, together with glycoproteins and glycosaminoglycans, it forms the glycocalyx that covers eukaryotic cell surfaces.
The role of GT1b-Trisialogangliosides is mainly associated with the nervous system. They are located especially in the axon membranes, where the molecules bind to myelin-associated glycoproteins. This interaction is crucial to regulating and maintaining axon-myelin stability.
Trisialoganglioside-GT1b is studied to be present in metastatic brain tumor tissues. Immunohistochemical analyses have confirmed the occurrence of the ganglioside in both cancer cell membrane and cytosol. Thus, Trisialoganglioside-GT1b is a brain metastasis-associated ganglioside.
Avanti Research provides the highest-quality experimental lipid products, amongst which is C18:0 Trisialoganglioside-GT1b, to meet your research needs.
C95H174N8O47
C 52.33%, H 8.04%, N 5.14%, O 34.49%
CAS Registry Number is a Registered Trademark of the American Chemical Society
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