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860065 | Ganglioside GM1 (Ovine Brain)

GM1 Ganglioside (Brain, Ovine-Sodium Salt)

Ganglioside GM1 (Ovine Brain)

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Size SKU Packaging Price
1mg 860065P-1mg 860065P-1mg 1 x 1mg $213.44
5mg 860065P-5mg 860065P-5mg 1 x 5mg $434.15
10mg 860065P-10mg 860065P-10mg 1 x 10mg $739.10
25mg 860065P-25mg 860065P-25mg 1 x 25mg $1,646.75
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Info

Ganglioside GM1 (Ovine Brain)

GM1 Ganglioside (Brain, Ovine-Sodium Salt)

Data
Hygroscopic
No
Light Sensitive
No
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
37758-47-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
1568.805
Synonyms
110952
Downloads
References

Bucciantini M, Leri M, Stefani M, Melki R, Zecchi-Orlandini S, Nosi D. The Amphipathic GM1 Molecule Stabilizes Amyloid Aggregates, Preventing their Cytotoxicity. Biophys J. 2020 Jul 21;119(2):326-336. doi: 10.1016/j.bpj.2020.06.005. Epub 2020 Jun 12. PMID: 32579964; PMCID: PMC7376221.

 PubMed ID: 32579964

Ahyayauch H, de la Arada I, Masserini ME, Arrondo JLR, Goñi FM, Alonso A. The Binding of Aβ42 Peptide Monomers to Sphingomyelin/Cholesterol/Ganglioside Bilayers Assayed by Density Gradient Ultracentrifugation. Int J Mol Sci. 2020 Feb 29;21(5):1674. doi: 10.3390/ijms21051674. PMID: 32121399; PMCID: PMC7084322.

 PubMed ID: 32121399

Mojumdar EH, Grey C, Sparr E. Self-Assembly in Ganglioside‒Phospholipid Systems: The Co-Existence of Vesicles, Micelles, and Discs. Int J Mol Sci. 2019 Dec 20;21(1):E56. doi: 10.3390/ijms21010056. PMID: 31861839.

 PubMed ID: 31861839

Li N, Wang P, Liu X, Han C, Ren W, Li T, Li X, Tao F, Zhao Z. Developing IR-780 as a Novel Matrix for Enhanced MALDI MS Imaging of Endogenous High-Molecular-Weight Lipids in Brain Tissues. Anal Chem. 2019 Dec 17;91(24):15873-15882. doi: 10.1021/acs.analchem.9b04315. Epub 2019 Nov 26.

 PubMed ID: 31718156

Owen MC, Karner A, Šachl R, Preiner J, Amaro M, Vácha R. Force Field Comparison of GM1 in a DOPC Bilayer Validated with AFM and FRET Experiments. J Phys Chem B. 2019 Aug 26. doi: 10.1021/acs.jpcb.9b05095. [Epub ahead of print]

 PubMed ID: 31397569

Bode DC, Freeley M, Nield J, Palma M, Viles JH. Amyloid-β oligomers have a profound detergent-like effect on lipid membrane bilayers, imaged by atomic force and electron microscopy. J Biol Chem. 2019 May 10;294(19):7566-7572. doi: 10.1074/jbc.AC118.007195. Epub 2019 Apr 3.

 PubMed ID: 30948512

Shi JM, Lv JM, Gao BX, Zhang L, Ji SR. Endosomal pH favors shedding of membrane-inserted amyloid-β peptide. Protein Sci. 2019 May;28(5):889-899. doi: 10.1002/pro.3596. Epub 2019 Mar 15.

 PubMed ID: 30825227

Gaspar R, Pallbo J, Weininger U, Linse S, Sparr E. Reprint of "Ganglioside lipids accelerate α-synuclein amyloid formation". Biochim Biophys Acta Proteins Proteom. 2019 May;1867(5):508-518. doi: 10.1016/j.bbapap.2019.02.003. Epub 2019 Mar 13.

 PubMed ID: 30878495

Ewald M, Henry S, Lambert E, Feuillie C, Bobo C, Cullin C, Lecomte S, Molinari M. High speed atomic force microscopy to investigate the interactions between toxic Aβ1-42 peptides and model membranes in real time: impact of the membrane composition. Nanoscale. 2019 Apr 11;11(15):7229-7238. doi: 10.1039/c8nr08714h.

 PubMed ID: 30924478

Hirai M, Ajito S, Takahashi K, Iwasa T, Li X, Wen D, Kawai-Hirai R, Ohta N, Igarashi N, Shimizu N. Structure of Ultrafine Bubbles and Their Effects on Protein and Lipid Membrane Structures Studied by Small- and Wide-Angle X-ray Scattering. J Phys Chem B. 2019 Apr 11. doi: 10.1021/acs.jpcb.9b00837. [Epub ahead of print]

 PubMed ID: 30920836

Sapoń K, Janas T, Sikorski AF, Janas T. Polysialic acid chains exhibit enhanced affinity for ordered regions of membranes. Biochim Biophys Acta Biomembr. 2019 Jan;1861(1):245-255. doi: 10.1016/j.bbamem.2018.07.008. Epub 2018 Jul 21.

 PubMed ID: 30040924

Hoshino T, Mahmood MI, Mori K, Matsuzaki K. Binding and aggregation mechanism of amyloid β-peptides onto the GM1 ganglioside-containing lipid membrane. J Phys Chem B. 2013 Jul 11;117(27):8085-94. doi: 10.1021/jp4029062. Epub 2013 May 31.

 PubMed ID: 23688073

Miyazaki Y, Aoki M, Yano Y, Matsuzaki K. Interaction of antimicrobial peptide magainin 2 with gangliosides as a target for human cell binding. Biochemistry. 2012 Dec 21;51(51):10229-35. doi: 10.1021/bi301470h. Epub 2012 Dec 11.

 PubMed ID: 23194027
Certificates of Analysis

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