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858122 | 16:0 Lyso PG

1-palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)

16:0 Lyso PG

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500mg 858122P-500mg 858122P-500mg 1 x 500mg $275.00
1g 858122P-1g 858122P-1g 1 x 1g $475.39
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Info

16:0 Lyso PG

1-palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)

Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C22H44O9PNa
Percent Composition
C 52.17%, H 8.76%, Na 4.54%, O 28.43%, P 6.11%
Purity
>99% LPG; may contain up to 10% of the 2-LPG isomer
Stability
1 year
Storage Temperature
-20°C
CAS Number
326495-22-1
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
506.543
Exact Mass
506.262
Synonyms
1-hexadecanoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt)
PG(16:0/0:0)
110711
CMC
0.6mM
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References

Siriwardane DA, Wang C, Jiang W, Mudalige T. Quantification of phospholipid degradation products in liposomal pharmaceutical formulations by ultra performance liquid chromatography-mass spectrometry (UPLC-MS). Int J Pharm. 2020 Jan 24;578:119077. doi: 10.1016/j.ijpharm.2020.119077. Epub ahead of print. PMID: 31988036.

 PubMed ID: 31988036

Shi Q, Jin S, Xiang X, Tian J, Huang R, Li S, Chen C, Xu H, Song C. The metabolic change in serum lysoglycerophospholipids intervened by triterpenoid saponins from Kuding tea on hyperlipidemic mice. Food Funct. 2019 Dec 11;10(12):7782-7792. doi: 10.1039/c9fo02142f.

 PubMed ID: 31782452

Yan Y, Du Z, Chen C, Li J, Xiong X, Zhang Y, Jiang H. Lysophospholipid profiles of apolipoprotein E-deficient mice reveal potential lipid biomarkers associated with atherosclerosis progression using validated UPLC-QTRAP-MS/MS-based lipidomics approach. J Pharm Biomed Anal. 2019 Jul 15;171:148-157. doi: 10.1016/j.jpba.2019.03.062. Epub 2019 Apr 5.

 PubMed ID: 30999225

Pedersen JN, Jiang Z, Christiansen G, Lee JC, Pedersen JS, Otzen DE. Lysophospholipids induce fibrillation of the repeat domain of Pmel17 through intermediate core-shell structures. Biochim Biophys Acta Proteins Proteom. 2018 Nov 22. pii: S1570-9639(18)30205-X. doi: 10.1016/j.bbapap.2018.11.007. [Epub ahead of print].

PubMed ID: 30471451

Zhao R, Kennedy K, De Blas GA, Orta G, Pavarotti MA, Arias RJ, de la Vega-Beltrán JL, Li Q, Dai H, Perozo E, Mayorga LS, Darszon A, Goldstein SAN. Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor. Proc Natl Acad Sci U S A. 2018 Dec 11;115(50):E11847-E11856. doi: 10.1073/pnas.1816189115. Epub 2018 Nov 26.

 PubMed ID: 30478045

Stafford, R.E., Fanni, T., Dennis, E.A. (1989) Interfacial properties and critical micelle concentration of lysophospholipids. Biochemistry. 28(12):5113-20. [PubMed]

 PubMed ID: 2669968

Huang, P., Liu, Q., Scarborough, G.A. (1998) Lysophosphatidylglycerol: a novel effective detergent for solubilizing and purifying the cystic fibrosis transmembrane conductance regulator. Anal Biochem. 259(1):89-97. [PubMed]

 PubMed ID: 9606148
Certificates of Analysis

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