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855775 | 18:0 Lyso PC

1-stearoyl-2-hydroxy-sn-glycero-3-phosphocholine

18:0 Lyso PC

Chloroform

Size SKU Packaging Price
25mg 855775C-25mg 855775C-25mg 1 x 25mg 10mg/mL 2.5mL $149.50
500mg 855775C-500mg 855775C-500mg 1 x 500mg 25mg/mL 20mL $300.00
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Powder

Size SKU Packaging Price
25mg 855775P-25mg 855775P-25mg 1 x 25mg $149.50 149.5
200mg 855775P-200mg 855775P-200mg 1 x 200mg $192.00 192
500mg 855775P-500mg 855775P-500mg 1 x 500mg $300.00 300
1g 855775P-1g 855775P-1g 1 x 1g $526.77 526.77
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Info

18:0 Lyso PC

1-stearoyl-2-hydroxy-sn-glycero-3-phosphocholine

Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C26H54NO7P
Percent Composition
C 59.63%, H 10.39%, N 2.67%, O 21.39%, P 5.91%
Purity
>99% LPC; may contain up to 10% of the 2-LPC isomer
Stability
1 Years
Storage Temperature
-20°C
CAS Number
19420-57-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
523.683
Exact Mass
523.364
Synonyms
1-octadecanoyl-sn-glycero-3-phosphocholine
PC(18:0/0:0)
110687
CMC
0.4µM
Downloads
References

Charron DM, Yousefalizadeh G, Buzzá HH, Rajora MA, Chen J, Stamplecoskie KG, Zheng G. Photophysics of J-Aggregating Porphyrin-Lipid Photosensitizers in Liposomes: Impact of Lipid Saturation. Langmuir. 2020 May 11. doi: 10.1021/acs.langmuir.0c00843. Epub ahead of print. PMID: 32338515.

 PubMed ID: 32338515

Park JM, Kim MJ, Noh JY, Yun TG, Kang MJ, Lee SG, Yoo BC, Pyun JC. Simultaneous Analysis of Multiple Cancer Biomarkers Using MALDI-TOF Mass Spectrometry Based on a Parylene-Matrix Chip. J Am Soc Mass Spectrom. 2020 Apr 1;31(4):917-926. doi: 10.1021/jasms.9b00102. Epub 2020 Mar 24. PMID: 32154716.

 PubMed ID: 32154716

Knuplez E, Curcic S, Theiler A, Bärnthaler T, Trakaki A, Trieb M, Holzer M, Heinemann A, Zimmermann R, Sturm EM, Marsche G. Lysophosphatidylcholines inhibit human eosinophil activation and suppress eosinophil migration in vivo. Biochim Biophys Acta Mol Cell Biol Lipids. 2020 Jul;1865(7):158686. doi: 10.1016/j.bbalip.2020.158686. Epub 2020 Mar 11. PMID: 32171907.

 PubMed ID: 32171907

Siriwardane DA, Wang C, Jiang W, Mudalige T. Quantification of phospholipid degradation products in liposomal pharmaceutical formulations by ultra performance liquid chromatography-mass spectrometry (UPLC-MS). Int J Pharm. 2020 Jan 24;578:119077. doi: 10.1016/j.ijpharm.2020.119077. Epub ahead of print. PMID: 31988036.

 PubMed ID: 31988036

Kari OK , Ndika J , Parkkila P , Louna A , Lajunen T , Puustinen A , Viitala T , Alenius H , Urtti A . In situ analysis of liposome hard and soft protein corona structure and composition in a single label-free workflow. Nanoscale. 2020 Jan 23;12(3):1728-1741. doi: 10.1039/c9nr08186k. PMID: 31894806.

 PubMed ID: 31894806

Chagas-Lima AC, Pereira MG, Fampa P, Lima MS, Kluck GEG, Atella GC. Bioactive lipids regulate Trypanosoma cruzi development. Parasitol Res. 2019 Sep;118(9):2609-2619. doi: 10.1007/s00436-019-06331-9. Epub 2019 Jul 2.

 PubMed ID: 31267245

Cai H, Cao T, Li N, Fang P, Xu P, Wu X, Zhang B, Xiang D. Quantitative monitoring of a panel of stress-induced biomarkers in human plasma by liquid chromatography-tandem mass spectrometry: an application in a comparative study between depressive patients and healthy subjects. Anal Bioanal Chem. 2019 Jun 14. doi: 10.1007/s00216-019-01956-2. [Epub ahead of print]

 PubMed ID: 31201457

Daniel J. Stephenson, H. Patrick MacKnight, L. Alexis Hoeferlin, Margaret A. Park, Jeremy C. Allegood, Christopher L. Cardona, and Charles E. Chalfant. A rapid and adaptable lipidomics method for quantitative UPLC-mass spectrometric analysis of phosphatidylethanolamine and phosphatidylcholine in vitro, and in cells. Anal. Methods, 2019,11, 1765-1776. doi: 10.1039/C9AY00052F

Cho Y, Woo JH, Kwon OS, Yoon SS, Son J. Alterations in phospholipid profiles of erythrocytes deep-frozen without cryoprotectants. Drug Test Anal. 2019 Apr 5. doi: 10.1002/dta.2600. [Epub ahead of print]

 PubMed ID: 30950199

Lee CW, Lee D, Lee EM, Park SJ, Ji DY, Lee DY, Jung YC. Lipidomic profiles disturbed by the internet gaming disorder in young Korean males. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 May 1;1114-1115:119-124. doi: 10.1016/j.jchromb.2019.03.027. Epub 2019 Mar 23.

 PubMed ID: 30951964

Sadeghi N, Kok RJ, Bos C, Zandvliet M, Geerts WJC, Storm G, Moonen CTW, Lammers T, Deckers R. Hyperthermia-triggered release of hypoxic cell radiosensitizers from temperature-sensitive liposomes improves radiotherapy efficacy in vitro. Nanotechnology. 2019 Mar 5;30(26):264001. doi: 10.1088/1361-6528/ab0ce6. [Epub ahead of print]

 PubMed ID: 30836341

Kontturi LS, van den Dikkenberg J, Urtti A, Hennink WE, Mastrobattista E. Light-Triggered Cellular Delivery of Oligonucleotides. Pharmaceutics. 2019 Feb 21;11(2). pii: E90. doi: 10.3390/pharmaceutics11020090.

 PubMed ID: 30795565

Quan H, Bae HB, Hur YH, Lee KH, Lee CH, Jang EA, Jeong S. Stearoyl lysophosphatidylcholine inhibits LPS-induced extracellular release of HMGB1 through the G2A/calcium/CaMKKβ/AMPK pathway. Eur J Pharmacol. 2019 Feb 21;852:125-133. doi: 10.1016/j.ejphar.2019.02.038. [Epub ahead of print]

 PubMed ID: 30797785

Qin Q, Wang B, Wang J, Chang M, Xia T, Shi X, Xu G. A comprehensive strategy for studying protein-metabolite interactions by metabolomics and native mass spectrometry. Talanta. 2019 Mar 1;194:63-72. doi: 10.1016/j.talanta.2018.10.010. Epub 2018 Oct 10.

 PubMed ID: 30609583

Zhang Q, Xu H, Liu R, Gao P, Yang X, Jin W, Zhang Y, Bi K, Li Q. A Novel Strategy for Targeted Lipidomics Based on LC-Tandem-MS Parameters Prediction, Quantification, and Multiple Statistical Data Mining: Evaluation of Lysophosphatidylcholines as Potential Cancer Biomarkers. Anal Chem. 2019 Mar 5;91(5):3389-3396. doi: 10.1021/acs.analchem.8b04715. Epub 2019 Feb 12.

 PubMed ID: 30689358

S. Katsuta, T. Okano, H. Suzuki. Reagent Handling and Delivery System Using Cell-Sized Liposomes. 2018 IEEE 13th Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). 2018 Dec 06. doi: 10.1109/NEMS.2018.8556884

Ditz T, Schnapka-Hille L, Noack N, Dorow J, Ceglarek U, Niederwieser D, Schiller J, Fuchs B, Cross M. Phospholipase A2 products predict the hematopoietic support capacity of horse serum. Differentiation. 2019 Jan - Feb;105:27-32. doi: 10.1016/j.diff.2018.12.002. Epub 2018 Dec 6.

 PubMed ID: 30554008

Stafford, R.E., Fanni, T., Dennis, E.A. (1989) Interfacial properties and critical micelle concentration of lysophospholipids. Biochemistry. 28(12):5113-20.

 PubMed ID: 2669968
Certificates of Analysis

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