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855575 | 14:0 Lyso PC

1-myristoyl-2-hydroxy-sn-glycero-3-phosphocholine

14:0 Lyso PC

Chloroform

Size SKU Packaging Price
200mg 855575C-200mg 855575C-200mg 2 x 100mg 25mg/mL 4mL $192.00
1g 855575C-1g 855575C-1g 2 x 500mg 25mg/mL 20mL $526.77
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Powder

Size SKU Packaging Price
25mg 855575P-25mg 855575P-25mg 1 x 25mg $149.50 149.5
200mg 855575P-200mg 855575P-200mg 1 x 200mg $192.00 192
500mg 855575P-500mg 855575P-500mg 1 x 500mg $300.00 300
1g 855575P-1g 855575P-1g 1 x 1g $526.77 526.77
Request Bulk Pricing
Info

14:0 Lyso PC

1-myristoyl-2-hydroxy-sn-glycero-3-phosphocholine

Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C22H46NO7P
Percent Composition
C 56.51%, H 9.92%, N 3.00%, O 23.95%, P 6.62%
Purity
>99% LPC; may contain up to 10% of the 2-LPC isomer
Stability
1 Years
Storage Temperature
-20°C
CAS Number
20559-16-4
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
467.577
Exact Mass
467.301
Synonyms
1-tetradecanoyl-sn-glycero-3-phosphocholine
PC(14:0/0:0)
110684
CMC
0.043 - 0.090mM
Downloads
References

Valdivia AO, Agarwal PK, Bhattacharya SK. Myelin Basic Protein Phospholipid Complexation Likely Competes with Deimination in Experimental Autoimmune Encephalomyelitis Mouse Model. ACS Omega. 2020 Jun 16;5(25):15454-15467. doi: 10.1021/acsomega.0c01590. PMID: 32637820; PMCID: PMC7331039.

 PubMed ID: 32637820

Bouillet B, Gautier T, Denimal D, Samson M, Masson D, Pais de Barros JP, Maquart G, Xolin M, Grosfeld A, Dalle H, Vergès B, Moldes M, Fève B. Glucocorticoids impair HDL-mediated cholesterol efflux besides increased HDL cholesterol concentration - a proof of concept. Eur J Endocrinol. 2020 Jun 1:EJE-20-0477. doi: 10.1530/EJE-20-0477. Epub ahead of print. PMID: 32570209.

Senders ML, Meerwaldt AE, van Leent MMT, Sanchez-Gaytan BL, van de Voort JC, Toner YC, Maier A, Klein ED, Sullivan NAT, Sofias AM, Groenen H, Faries C, Oosterwijk RS, van Leeuwen EM, Fay F, Chepurko E, Reiner T, Duivenvoorden R, Zangi L, Dijkhuizen RM, Hak S, Swirski FK, Nahrendorf M, Pérez-Medina C, Teunissen AJP, Fayad ZA, Calcagno C, Strijkers GJ, Mulder WJM. Probing myeloid cell dynamics in ischaemic heart disease by nanotracer hot-spot imaging. Nat Nanotechnol. 2020 May;15(5):398-405. doi: 10.1038/s41565-020-0642-4. Epub 2020 Apr 20. PMID: 32313216.

 PubMed ID: 32313216

Nagano N, Honjo M, Kawaguchi M, Nishimasu H, Nureki O, Kano K, Aoki J, Komatsu T, Okabe T, Kojima H, Nagano T, Aihara M. Development of a Novel Intraocular-Pressure-Lowering Therapy Targeting ATX. Biol Pharm Bull. 2019;42(11):1926-1935. doi: 10.1248/bpb.b19-00567.

 PubMed ID: 31685776

Uranbileg B, Ito N, Kurano M, Saigusa D, Saito R, Uruno A, Kano K, Ikeda H, Yamada Y, Sumitani M, Sekiguchi M, Aoki J, Yatomi Y. Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model. Sci Rep. 2019 Nov 12;9(1):16578. doi: 10.1038/s41598-019-52999-5.

 PubMed ID: 31719574

Vaz FM, McDermott JH, Alders M, Wortmann SB, Kölker S, Pras-Raves ML, Vervaart MAT, van Lenthe H, Luyf ACM, Elfrink HL, Metcalfe K, Cuvertino S, Clayton PE, Yarwood R, Lowe MP, Lovell S, Rogers RC; Deciphering Developmental Disorders Study, van Kampen AHC, Ruiter JPN, Wanders RJA, Ferdinandusse S, van Weeghel M, Engelen M, Banka S. Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia. Brain. 2019 Nov 1;142(11):3382-3397. doi: 10.1093/brain/awz291.

 PubMed ID: 31637422

Xu G, Qian Y, Zheng H, Qiao S, Yan D, Lu L, Wu L, Yang X, Luo Q, Zhang Z. Long-Distance Tracing of the Lymphatic System with a Computed Tomography/Fluorescence Dual-Modality Nanoprobe for Surveying Tumor Lymphatic Metastasis. Bioconjug Chem. 2019 Apr 17;30(4):1199-1209. doi: 10.1021/acs.bioconjchem.9b00144. Epub 2019 Apr 1.

 PubMed ID: 30888794

Huffnagel IC, Dijkgraaf MGW, Janssens GE, van Weeghel M, van Geel BM, Poll-The BT, Kemp S, Engelen M. Disease progression in women with X-linked adrenoleukodystrophy is slow. Orphanet J Rare Dis. 2019 Feb 7;14(1):30. doi: 10.1186/s13023-019-1008-6.

 PubMed ID: 30732635

Stafford, R.E., Fanni, T., Dennis, E.A. (1989) Interfacial properties and critical micelle concentration of lysophospholipids. Biochemistry. 28(12):5113-20. [PubMed]

PubMed ID: 2669968

Göbl, C., Dulle, M., Hohlweg, W., Grossauer, J., Falsone, S.F., Glatter, O., Zangger, K. (2010) Influence of phosphocholine alkyl chain length on peptide-micelle interactions and micellar size and shape. J Phys Chem B. 114:4717-24. [PubMed]

 PubMed ID: 20225847

Koehler, J., Sulistijo, E.S., Sakakura, M., Kim, H.J., Ellis, C.D., Sanders, C.R. (2010) Lysophospholipid micelles sustain the stability and catalytic activity of diacylglycerol kinase in the absence of lipids. Biochemistry. 49:7089-99. [PubMed]

 PubMed ID: 20666483

Vernier, G., Wang, J., Jennings, L.D., Sun, J., Fischer, A., Song, L., Collier, R.J. (2009) Solubilization and characterization of the anthrax toxin pore in detergent micelles. Protein Sci. 18:1882-95. [PubMed]

 PubMed ID: 19609933

Zeisig, R., Ress, A., Fichtner, I., Walther, W. (2003) Lipoplexes with alkylphospholipid as new helper lipid for efficient in vitro and in vivo gene transfer in tumor therapy. Cancer Gene Ther. 10:302-11. [PubMed]

 PubMed ID: 12679803
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