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855475 | 12:0 Lyso PC

1-lauroyl-2-hydroxy-sn-glycero-3-phosphocholine

12:0 Lyso PC

Chloroform

Size SKU Packaging Price
25mg 855475C-25mg 855475C-25mg 1 x 25mg 10mg/mL 2.5mL $162.50
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Powder

Size SKU Packaging Price
200mg 855475P-200mg 855475P-200mg 1 x 200mg $306.00 306
25mg 855475P-25mg 855475P-25mg 1 x 25mg $162.50 162.5
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Info

12:0 Lyso PC

1-lauroyl-2-hydroxy-sn-glycero-3-phosphocholine

Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula
C20H42NO7P
Percent Composition
C 54.65%, H 9.63%, N 3.19%, O 25.48%, P 7.05%
Purity
>99% LPC; may contain up to 10% of the 2-LPC isomer
Stability
1 Years
Storage Temperature
-20°C
CAS Number
20559-18-6
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
439.524
Exact Mass
439.27
Synonyms
1-dodecanoyl-sn-glycero-3-phosphocholine
PC(12:0/0:0)
CMC
0.4 - 0.9mM
Downloads
References

Wen SY, Chen YY, Lu JX, Liang QQ, Shi H, Wu Q, Yao ZH, Zhu Y, Jiang MM. Modulation of hepatic lipidome by rhodioloside in high-fat diet fed apolipoprotein E knockout mice. Phytomedicine. 2020 Apr;69:152690. doi: 10.1016/j.phymed.2018.09.225. Epub 2018 Sep 27. PMID: 30389273.

 PubMed ID: 30389273

Miaomiao Jiang, Jingyu Ni, Yuanlin Cao, Xiaoxue Xing, Qian Wu, and Guanwei Fan, “Astragaloside IV Attenuates Myocardial Ischemia-Reperfusion Injury from Oxidative Stress by Regulating Succinate, Lysophospholipid Metabolism, and ROS Scavenging System,” Oxidative Medicine and Cellular Longevity, vol. 2019, Article ID 9137654, 17 pages, 2019. doi: 10.1155/2019/9137654.

Quan H, Bae HB, Hur YH, Lee KH, Lee CH, Jang EA, Jeong S. Stearoyl lysophosphatidylcholine inhibits LPS-induced extracellular release of HMGB1 through the G2A/calcium/CaMKKβ/AMPK pathway. Eur J Pharmacol. 2019 Feb 21;852:125-133. doi: 10.1016/j.ejphar.2019.02.038. [Epub ahead of print]

 PubMed ID: 30797785

Pedersen JN, Jiang Z, Christiansen G, Lee JC, Pedersen JS, Otzen DE. Lysophospholipids induce fibrillation of the repeat domain of Pmel17 through intermediate core-shell structures. Biochim Biophys Acta Proteins Proteom. 2018 Nov 22. pii: S1570-9639(18)30205-X. doi: 10.1016/j.bbapap.2018.11.007. [Epub ahead of print]

 PubMed ID: 30471451

Stafford, R.E., Fanni, T., Dennis, E.A. (1989) Interfacial properties and critical micelle concentration of lysophospholipids. Biochemistry. 28(12):5113-20.

 PubMed ID: 2669968

Stafford RE, Fanni T, Dennis EA. Interfacial properties and critical micelle concentration of lysophospholipids. Biochemistry. 1989 Jun 13;28(12):5113-20.

 PubMed ID: 2669968
Certificates of Analysis

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