Section Menu

850500 | CHAPS

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

CHAPS

Powder

Size SKU Packaging Price
1g 850500P-1g 850500P-1g 1 x 1g $59.54
Request Bulk Pricing
Info

CHAPS

3-[(3-Cholamidopropyl)dimethylammonio]-1-propanesulfonate

CHAPS is a nondenaturing zwitterionic detergent for membrane biochemistry. Useful for solubilizing membrane proteins and breaking protein-protein interactions. CHAPS’ small micellar molecular weight (6,150; aggregation number = 10) and high critical micelle concentration (6-10 mM) allow it to be removed from samples by dialysis. It is also suitable for protein solubilization for isoelectric focusing and two-dimensional electrophoresis. CHAPS is commonly used for non-denaturing (without urea) IEF and has been shown to give excellent resolution of some subcellular preparations and plant proteins. Concentrations between 2-4% (w/v) are typically used in an IEF gel.
Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C32H58N2O7S
Percent Composition
C 62.51%, H 9.51%, N 4.56%, O 18.21%, S 5.21%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
75621-03-3
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
614.877
Exact Mass
614.396
CMC
6 mM (20-25°C)
Downloads
References

Kot EF, Arseniev AS, Mineev KS. On the behavior of most widely spread lipids in isotropic bicelles. Langmuir. 2018 Jun 20. doi: 10.1021/acs.langmuir.8b01454. [Epub ahead of print]

 PubMed ID: 29924628

Cordwell, S.J. (2008) Sequential extraction of proteins by chemical reagents. Methods Mol Biol. 424:139-46.

PubMed ID: 18369859

Kot EF, Goncharuk SA, Arseniev AS, Mineev KS. Phase Transitions in Small Isotropic Bicelles. Langmuir. 2018 Mar 6. doi: 10.1021/acs.langmuir.7b03610.

 PubMed ID: 29486112
Certificates of Analysis

Related Products

850545
LDAO LDAO Buy Now
850501
CHAPSO CHAPSO Buy Now

Cart

Item Price Qty.
${ item.sku }
Base Price: $${ (item.price - (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150))).toFixed(2) }
Custom Packaging: +${ (item.options.custompackaging * 4.2 + (item.options.custompackaging > 50 ? 250 : 150)).toFixed(2) }
Change Custom Packaging 		${ item.salePriceAsCurrency }
Subtotal: ${ cart.itemSubtotal|money }
${ adjustment.type }: ${ adjustment.name } ${ adjustment.amountAsCurrency }
${ adjustment.name } ${ adjustment.amountAsCurrency }
Order Total: ${ cart.totalPriceAsCurrency }
Have a promo code? Enter it in your cart to apply your discount and enjoy the savings on your purchase! Finalize Cart