16:0-18:1 PC (POPC) A80557 (Previously 850457) 1-palmitoyl-2-oleoyl-glycero-3-phosphocholine

1-palmitoyl-2-oleoyl-glycero-3-phosphocholine, or 16:0-18:1 PC (POPC), is a mixed-chain phospholipid featuring a 16-carbon saturated (palmitoyl) acyl chain at the sn-1 position and an 18-carbon monounsaturated (oleoyl) acyl chain at the sn-2 position. Thanks to a ~–2°C phase transition temperature and its physiological relevance, POPC is widely used in membrane biophysics, liposome formulations, and cell model systems.

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Product details

Product Type

Lipids

Product Category

Phospholipids - PC & LPC - Mixed Acyl

Application

POPC is a major lipid in eukaryotic cell membranes and is common in model membrane systems to imitate physiological conditions. Another notable aspect of this phospholipid is its balance between fluidity and stability, which allows it to be incorporated into drug delivery systems and lipid-based nanoparticles (LNPs). 16:0-18:1 PC (POPC) supports membrane protein integration, lipid raft research, and ion channel studies. These applications make it a key lipid in structural and functional membrane research. POPC has also contributed to vesicle fusion and structural lipid analyses through its integral functions in bilayer mechanics, lipid mixing, and membrane curvature studies.

Data

Hygroscopic	Yes
Light sensitive	No
Molecular formula	C₄₂H₈₂NO₈P
Percent composition	C 66.37%, H 10.87%, N 1.84%, O 16.84%, P 4.08%
Purity	>99%
Stability	1 Year
Storage temperature	-20°C
CAS number	26853-31-6 CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula weight	760.076
Exact mass	759.578
Synonyms	1-hexadecanoyl-2--(9Z-octadecenoyl)-sn-glycero-3-phosphocholine POPC PC(16:0/18:1(9Z)) 770557
Transition temperature	-2°C
Solubility in different solvents	Soluble in ethanol at 5mg/mL, soluble in DMSO at 5mg/mL, soluble in Chloroform:Methanol:Water at 5mg/mL

Certificates of Analysis

850457 - ChemDraw File
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ChemDraw File

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850457C - Safety Data Sheet
English: 298.0 KB

Safety Data Sheet

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