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850335 | 12:0 PC (DLPC)

1,2-dilauroyl-sn-glycero-3-phosphocholine

12:0 PC (DLPC)

Chloroform

Size SKU Packaging Price
25mg 850335C-25mg 850335C-25mg 1 x 25mg 10mg/mL 2.5mL $93.00
200mg 850335C-200mg 850335C-200mg 2 x 100mg 25mg/mL 4mL $154.00
500mg 850335C-500mg 850335C-500mg 1 x 500mg 25mg/mL 20mL $280.00
Request Bulk Pricing

Powder

Size SKU Packaging Price
25mg 850335P-25mg 850335P-25mg 1 x 25mg $93.00 93
200mg 850335P-200mg 850335P-200mg 1 x 200mg $154.00 154
500mg 850335P-500mg 850335P-500mg 1 x 500mg $280.00 280
1g 850335P-1g 850335P-1g 1 x 1g $436.59 436.59
Request Bulk Pricing
Info

12:0 PC (DLPC)

1,2-dilauroyl-sn-glycero-3-phosphocholine

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC's. All of the products are purified by HPLC, and special precautions are taken to protect the products from oxidization and hydrolysis. Several of these products are manufactured under the current guidelines of Good Manufacturing Practice and are available for pharmaceutical use. If you have a requirement for a choline derivative not found on our list, please call us: custom synthesis is one of our specialties.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C32H64NO8P
Percent Composition
C 61.81%, H 10.37%, N 2.25%, O 20.58%, P 4.98%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
18194-25-7
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
621.826
Exact Mass
621.437
Synonyms
1,2-didodecanoyl-sn-glycero-3-phosphocholine
DLPC
PC(12:0/12:0)
Transition Temp
-2°C
CMC
90nM
Downloads
References

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Ruokonen SK, Ekholm FS, Wiedmer SK. Assessing the Interactions of Auristatin Derivatives with Mixed Phospholipid-Sodium Dodecyl Sulfate Aggregate Dispersions. Langmuir. 2019 Apr 3. doi: 10.1021/acs.langmuir.9b00116. [Epub ahead of print]

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Li Q, Li C, Mu W, Han X. Topological Defect-Driven Buckling of Phospholipid Bicelles to Cones for Micromotors with Modulated Heading Pathways. ACS Nano. 2019 Mar 13. doi: 10.1021/acsnano.9b00086. [Epub ahead of print]

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Afrose F, McKay MJ, Mortazavi A, Suresh Kumar V, Greathouse DV, Koeppe RE 2nd. Transmembrane Helix Integrity versus Fraying To Expose Hydrogen Bonds at a Membrane-Water Interface. Biochemistry. 2019 Feb 12;58(6):633-645. doi: 10.1021/acs.biochem.8b01119. Epub 2019 Jan 3.

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Sherratt SCR, Villeneuve P, Durand E, Mason RP. Rosmarinic acid and its esters inhibit membrane cholesterol domain formation through an antioxidant mechanism based, in nonlinear fashion, on alkyl chain length. Biochim Biophys Acta Biomembr. 2019 Mar 1;1861(3):550-555. doi: 10.1016/j.bbamem.2018.12.016. Epub 2018 Dec 21.

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Sampa Sarkar, Nhiem Tran, Md Harunur Rashid, Tu C. Le, Irene Yarovsky, Charlotte E. Conn, and Calum J. Drummond. Toward Cell Membrane Biomimetic Lipidic Cubic Phases: A High-Throughput Exploration of Lipid Compositional Space. ACS Appl. Bio Mater., 2019, 2 (1), pp 182–195. doi: 10.1021/acsabm.8b00539

Iemoto T, Nishiumi S, Kobayashi T, Fujigaki S, Hamaguchi T, Kato K, Shoji H, Matsumura Y, Honda K, Yoshida M. Serum level of octanoic acid predicts the efficacy of chemotherapy for colorectal cancer. Oncol Lett. 2019 Jan;17(1):831-842. doi: 10.3892/ol.2018.9731. Epub 2018 Nov 19.

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Vignoni M, Urrutia MN, Junqueira HC, Greer A, Reis A, Baptista MS, Itri R, Thomas AH. Photo-Oxidation of Unilamellar Vesicles by a Lipophilic Pterin: Deciphering Biomembrane Photodamage. Langmuir. 2018 Dec 18;34(50):15578-15586. doi: 10.1021/acs.langmuir.8b03302. Epub 2018 Dec 4.

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Seki N, Mori K, Kitamura T, Miyamoto M, Kihara A. Yeast Mpo1 Is a Novel Dioxygenase That Catalyzes the α-Oxidation of a 2-Hydroxy Fatty Acid in an Fe2+-Dependent Manner. Mol Cell Biol. 2019 Feb 15;39(5). pii: e00428-18. doi: 10.1128/MCB.00428-18. Print 2019 Mar 1.

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Zhu C, Li Q, Dong M, Han X. Giant Unilamellar Vesicle Microarrays for Cell Function Study. Anal Chem. 2018 Dec 18;90(24):14363-14367. doi: 10.1021/acs.analchem.8b03825. Epub 2018 Nov 27.

 PubMed ID: 30481002

Mikyung Yu, Carleena A. Ortega, Kevin Si, Roberto Molinaro, Frederick J. Schoen, Renata F. C. Leitao, Xiaoding Xu, Morteza Mahmoudi, Suyeon Ahn,Jerry Liu, Phei Er Saw, In-Hyun Lee, Mirna M. B. Brayner, Azita Lotfi, Jinjun Shi, Peter Libby, Sangyong Jon, Omid C. Farokhzad. Nanoparticles targeting extra domain B of fibronectin−specific to the atherosclerotic lesion types III, IV, and V−enhance plaque detection and cargo delivery. 2018; 8(21): 6008-6024. doi: 10.7150/thno.24365

Zhu C, Li Q, Dong M, Han X. Giant Unilamellar Vesicle Microarrays for Cell Function Study. Anal Chem. 2018 Nov 27. doi: 10.1021/acs.analchem.8b03825. [Epub ahead of print]

 PubMed ID: 30481002

La Barbera G, Antonelli M, Cavaliere C, Cruciani G, Goracci L, Montone CM, Piovesana S, Laganà A, Capriotti AL. Delving into the Polar Lipidome by Optimized Chromatographic Separation, High-Resolution Mass Spectrometry, and Comprehensive Identification with Lipostar: Microalgae as Case Study. Anal Chem. 2018 Sep 24. doi: 10.1021/acs.analchem.8b03482. [Epub ahead of print]

 PubMed ID: 30204416

Inloes JM, Jing H, Cravatt BF. The Spastic Paraplegia-Associated Phospholipase DDHD1 Is a Primary Brain Phosphatidylinositol Lipase. Biochemistry. 2018 Sep 17. doi: 10.1021/acs.biochem.8b00810. [Epub ahead of print]

 PubMed ID: 30221923

Staton JA, Dungan SR. Mechanism of Time-Dependent Adsorption for Dilauroyl Phosphatidylcholine onto a Clean Air-Water Interface from a Dispersion of Vesicles. Langmuir. 2018 Aug 15. doi: 10.1021/acs.langmuir.8b00595. [Epub ahead of print]

 PubMed ID: 30109933

Meker S, Chin H, Sut TN, Cho NJ. Amyloid-β Peptide Triggers Membrane Remodeling in Supported Lipid Bilayers Depending on Their Hydrophobic Thickness. Langmuir. 2018 Jul 18. doi: 10.1021/acs.langmuir.8b01196. [Epub ahead of print]

 PubMed ID: 30021071

Beltramo PJ, Scheidegger L, Vermant J. Toward Realistic Large-Area Cell Membrane Mimics: Excluding Oil, Controlling Composition, and Including Ion Channels. Langmuir. 2018 May 14. doi: 10.1021/acs.langmuir.8b00837

 PubMed ID: 29715042

Tran N, Zhai J, Conn CE, Mulet X, Waddington LJ, Drummond CJ. Direct Visualization of the Structural Transformation between the Lyotropic Liquid Crystalline Lamellar and Bicontinuous Cubic Mesophase. J Phys Chem Lett. 2018 Jun 8:3397-3402. doi: 10.1021/acs.jpclett.8b01110. [Epub ahead of print]

 PubMed ID: 29809009
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