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850334 | MAPCHO™-10

n-decylphosphocholine

MAPCHO™-10

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1g 850334P-1g 850334P-1g 1 x 1g $328.13
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MAPCHO™-10

n-decylphosphocholine

n-decylphosphocholine is a structural analog of decanoyl lysophosphatidylcholine that is more stable to hydrolytic degradation. The lipid maybe used as a detergent for membrane protein solubilization and purification.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula
C15H34NO4P
Percent Composition
C 55.71%, H 10.60%, N 4.33%, O 19.79%, P 9.58%
Purity
>99%
Stability
1 Years
Storage Temperature
-20°C
CAS Number
70504-28-8
CAS Registry Number is a Registered Trademark of the American Chemical Society
Formula Weight
323.409
Exact Mass
323.223
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References

Horst R, Stanczak P, Serrano P, Wüthrich K. Translational diffusion measurements by microcoil NMR in aqueous solutions of the Fos-10 detergent-solubilized membrane protein OmpX. J Phys Chem B. 2012 Jun 14;116(23):6775-80. doi: 10.1021/jp212401w. Epub 2012 Feb 29. PMID: 22335573; PMCID: PMC3376199.

 PubMed ID: 22335573

Palladino P, Rossi F, Ragone R. Effective critical micellar concentration of a zwitterionic detergent: a fluorimetric study on n-dodecyl phosphocholine. J Fluoresc. 2010 Jan;20(1):191-6. doi: 10.1007/s10895-009-0537-0. Epub 2009 Sep 16. PMID: 19756982.

 PubMed ID: 19756982

Vasudevan SV, Schulz J, Zhou C, Cocco MJ. Protein folding at the membrane interface, the structure of Nogo-66 requires interactions with a phosphocholine surface. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):6847-51. doi: 10.1073/pnas.0911817107. Epub 2010 Mar 29. PMID: 20351248; PMCID: PMC2872388.

 PubMed ID: 20351248

Liang B, Tamm LK. Structure of outer membrane protein G by solution NMR spectroscopy. Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16140-5. doi: 10.1073/pnas.0705466104. Epub 2007 Oct 2. PMID: 17911261; PMCID: PMC2042175.

 PubMed ID: 17911261

Brunecky R, Lee S, Rzepecki PW, Overduin M, Prestwich GD, Kutateladze AG, Kutateladze TG. Investigation of the binding geometry of a peripheral membrane protein. Biochemistry. 2005 Dec 13;44(49):16064-71. doi: 10.1021/bi051127+. PMID: 16331966; PMCID: PMC2516348.

 PubMed ID: 16331966

Liu DZ, LeCluyse EL, Thakker DR. Dodecylphosphocholine-mediated enhancement of paracellular permeability and cytotoxicity in Caco-2 cell monolayers. J Pharm Sci. 1999 Nov;88(11):1161-8. doi: 10.1021/js990094e. PMID: 10564065.

 PubMed ID: 10564065
Certificates of Analysis

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